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Ligand · 7T8

7T8 · (3s,4r,4ar,6s,6as,12r,12as,12bs)-4-[(acetyloxy)methyl]-12-hydroxy-4,6A,12B-trimethyl-11-oxo-9-(pyridin-3-yl)-1,3,4,4A,5,6,6A,12,12A,12B-decahydro-2H,11H-naphtho[2, 1-b]pyrano[3,4-e]pyran-3,6-diyl diacetate

7T8, (3s,4r,4ar,6s,6as,12r,12as,12bs)-4-[(acetyloxy)methyl]-12-hydroxy-4,6A,12B-trimethyl-11-oxo-9-(pyridin-3-yl)-1,3,4,4A,5,6,6A,12,12A,12B-decahydro-2H,11H-naphtho[2, 1-b]pyrano[3,4-e]pyran-3,6-diyl diacetate (C31 H37 N O10, 583.6…

Component
7T8
Formula
C31 H37 N O10
Class
ligand
Structures
2
PDB entries
1

Binding sites

7T8 in 2 structures; the first of them:

  • 7N6Q · Structure of PPPA bound human ACAT2 · 7T8 A601 · binds PHE234, MET350, LEU351, ILE354, TYR391, TRP394, PHE427, SER430 and 10 more
  • 7N6Q · Structure of pppa bound human ACAT2 · 7T8 A601 · binds PHE234, MET350, LEU351, TYR391, TRP394, PHE427, SER430, ALA431 and 9 more

Residues it binds most

PHE 8, GLN 8, LEU 8, MET 8, TYR 8, ALA 8, HIS 8, SER 8, TRP 8, VAL 8 (residue and the binding sites it lines).

Found with

  • CLR · Cholesterol
  • OLA · Oleic acid

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