MolNFT v1 · #182608 · protein
Ubiquitin variant UBV.K.1 in complex with UBE2K
7MYF · Ubiquitin-conjugating enzyme E2 K: “Ubiquitin variant UBV.K.1 in complex with UBE2K”. X-ray diffraction, 1 pocket (best druggability 0.29). MolNFT v1 #182608 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 7MYF
- Type
- protein
- Length
- 339 residues
- Chains
- 3
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Ubiquitin-conjugating enzyme E2 K; Ubiquitin variant UBV.K.1; Ubiquitin
- EC
- 2.3.2.23
- UniProt
- P61086, P0CG47, P0CG48
- Pockets
- 1 · best druggability 0.29
Structure
x-ray diffraction · 3 distinct chains · 32% helix, 22% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Ubiquitin-conjugating enzyme E2 K (EC 2.3.2.23) | protein | 196 | 42% helix, 13% strand | P61086 |
| B | Ubiquitin variant UBV.K.1 | protein | 72 | 15% helix, 33% strand | P0CG47 |
| C | Ubiquitin | protein | 71 | 20% helix, 34% strand | P0CG48 |
Pockets
1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 64 | 0.29 | 0.74 | 13 | empty |
Interfaces
2 interfaces between chains.
- A–B · 497 Ų buried · 2 hydrogen bonds · protein-protein
- A–C · 102 Ų buried · 1 hydrogen bond · protein-protein
Compared structures
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P61086
- Every structure of UniProt P0CG47
- Every structure of UniProt P0CG48
- Elsewhere: RCSB PDB 7MYF · PDBe 7MYF · UniProt P61086 · UniProt P0CG47 · UniProt P0CG48
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