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MolNFT v1 · #182587 · protein

CD1C with antigen analogue 2

7MXF: “CD1C with antigen analogue 2”. X-ray diffraction, 4 ligands (ZQ4, D12, ZP7). MolNFT v1 #182587 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB
7MXF
Type
protein
Length
380 residues
Chains
2
Method
x-ray diffraction
Collection
MolNFT v1 / PDB
Contract
0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner
0x3396CDB397284571d12822B4ae1189a8E22AAAAA
UniProt
P29017, P29016, P61769
Ligands
ZQ4, D12, ZP7, NAG

Structure

x-ray diffraction · 2 distinct chains.

ChainMoleculeTypeResiduesSecondary structureUniProt
A—protein276—P29017, P29016
B—protein104—P61769

Ligands and binding sites

  • ZQ4 · 2,6-anhydro-1-deoxy-1-[(S)-hydroxy{[(4r,8s,12r,16r, 20S)-4,8,12,16,20-pentamethylheptacosyl]oxy}phosphoryl]-D-glycero-D-galacto-heptitol · ligand · chains A
  • D12 · Dodecane · ligand · chains A
  • ZP7 · (2S)-2,3-dihydroxypropyl hexadecanoate · ligand · chains A
  • NAG · 2-acetamido-2-deoxy-beta-D-glucopyranose · sugar · chains A
  • NHE · 2-[N-cyclohexylamino]ethane sulfonic acid · additive · chains A, B
  • MLA · Malonic acid · additive · chains A, B

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Compared structures

  • 7MXF · CD1c with antigen analogue 2 · the same entry in another collection · chain A against A, TM-score 1.00
  • P29017 · AlphaFold monomer V2.0 prediction for T-cell surface glycoprotein CD1C (P29017) · a predicted model of the same protein · chain A against A, TM-score 0.96
  • P61769 · AlphaFold monomer V2.0 prediction for beta-2-microglobulin (P61769) · a predicted model of the same protein · chain B against A, TM-score 0.93
  • P29016 · AlphaFold monomer V2.0 prediction for T-cell surface glycoprotein CD1B (P29016) · a predicted model of the same protein · chain A against A, TM-score 0.92

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