UniProt P29017
T-cell surface glycoprotein CD1c/T-cell surface glycoprotein CD1b chimeric protein (P29017)
T-cell surface glycoprotein CD1c/T-cell surface glycoprotein CD1b chimeric protein (UniProt P29017): 13 experimental structures and 1 predicted model on GenesisL1, 12 ligands bound, 21 pockets. Binding sites, druggability and…
- UniProt
- P29017
- Protein
- T-cell surface glycoprotein CD1c/T-cell surface glycoprotein CD1b chimeric…
- Experimental structures
- 13
- Predicted models
- 1
- Ligands
- 12
- Pockets
- 21 · 3 records with a druggable one
Structures
14 records of P29017 in the MolNFT archive: 13 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 3OV6 | CD1c in complex with MPM (mannosyl-beta1-phosphomycoketide) | x-ray diffraction | A | — | — |
| 3OV6 | CD1C in complex with mpm (mannosyl-BETA1-phosphomycoketide) | x-ray diffraction | A | — | — |
| 4ONO | CD1c in complex with PM (phosphomycoketide) | x-ray diffraction | A | — | — |
| 4ONO | CD1C in complex with pm (phosphomycoketide) | x-ray diffraction | A | — | — |
| 5C9J | Human CD1C with ligands in a' and F' channel | x-ray diffraction | A | — | — |
| 6C09 | Ternary crystal structure of the 3C8 TCR-CD1c-monoacylglycerol complex | x-ray diffraction | A | NAG, EKG, D10, K | 6 (best 0.85) |
| 6C09 | Ternary crystal structure of the 3C8 TCR-CD1C-monoacylglycerol complex | x-ray diffraction | A | NAG, EKG, D10, K | — |
| 6C15 | CD1C in complex with phosphatidylcholine | x-ray diffraction | A | NAG, D12, 6PL, NA, SO4 | — |
| 7MX4 | CD1c with antigen analogue 1 | x-ray diffraction | A | NAG, ZPD, D12, ZP7 | 6 (best 0.84) |
| 7MX4 | CD1C with antigen analogue 1 | x-ray diffraction | A | NAG, ZPD, D12, ZP7 | — |
| 7MXF | CD1C with antigen analogue 2 | x-ray diffraction | A | NAG, ZQ4, D12, ZP7 | — |
| 7MXH | CD1c with antigen analogue 3 | x-ray diffraction | A | NAG, ZQ7, D12, ZP7 | 9 (best 0.85) |
| 7MXH | CD1C with antigen analogue 3 | x-ray diffraction | A | NAG, ZQ7, D12, ZP7 | — |
| P29017 | AlphaFold monomer V2.0 prediction for T-cell surface glycoprotein CD1C (P29017) | predicted | A | — | — |
Ligands
- NAG · 2-acetamido-2-deoxy-beta-D-glucopyranose · in 8 records
- D12 · Dodecane · in 6 records
- ZP7 · (2S)-2,3-dihydroxypropyl hexadecanoate · in 5 records
- D10 · Decane · in 2 records
- EKG · (2R)-2,3-dihydroxypropyl hexadecanoate · in 2 records
- K · Potassium ion · in 2 records
- ZPD · (4S,8R,12S,16S,20S)-4,8,12,16,20-pentamethylheptacosyl (1R,2S,3S,4R,5R)-2,3,4-trihydroxy-5-(hydroxymethyl) cyclohexyl hydrogen (R)-phosphate · in 2 records
- ZQ7 · 2,6-anhydro-1-deoxy-1,1-difluoro-1-[(R)-hydroxy{[(4s, 8S,12S,16S,20S)-4,8,12,16,20-pentamethylheptacosyl]oxy}phosphoryl]-D-glycero-D-galacto-heptitol · in 2 records
- 6PL · (4S,7R)-4-hydroxy-N,N,N-trimethyl-9-oxo-7-[(palmitoyloxy)methyl]-3,5,8-trioxa-4-phosphahexacosan-1-aminium 4-oxide · in 1 record
- NA · Sodium ion · in 1 record
- SO4 · Sulfate ion · in 1 record
- ZQ4 · 2,6-anhydro-1-deoxy-1-[(S)-hydroxy{[(4r,8s,12r,16r, 20S)-4,8,12,16,20-pentamethylheptacosyl]oxy}phosphoryl]-D-glycero-D-galacto-heptitol · in 1 record
Experiment against prediction
- 6C09 chain A against the predicted model P29017: TM-score 0.97, RMSD 1.07 Å
- 6C09 chain A against the predicted model P29017: TM-score 0.97, RMSD 1.07 Å
- 5C9J chain A against the predicted model P29017: TM-score 0.97, RMSD 1.02 Å
- 6C15 chain A against the predicted model P29017: TM-score 0.96, RMSD 1.09 Å
- 7MXF chain A against the predicted model P29017: TM-score 0.96, RMSD 1.39 Å
- 7MX4 chain A against the predicted model P29017: TM-score 0.95, RMSD 1.46 Å
- 7MX4 chain A against the predicted model P29017: TM-score 0.95, RMSD 1.46 Å
- 7MXH chain A against the predicted model P29017: TM-score 0.93, RMSD 1.76 Å
- 7MXH chain A against the predicted model P29017: TM-score 0.93, RMSD 1.76 Å
- 5C9J chain A against the predicted model P29016: TM-score 0.93, RMSD 1.78 Å
Elsewhere
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.