MolNFT v1 · #181803 · protein
Human septin hexameric complex SEPT2G/SEPT6/SEPT7 by single particle cryo-EM
7M6J: “Human septin hexameric complex SEPT2G/SEPT6/SEPT7 by single particle cryo-EM”. Electron microscopy, 3 ligands (GDP, GTP, MG). MolNFT v1 #181803 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 7M6J
- Type
- protein
- Length
- 1,614 residues
- Chains
- 6
- Method
- electron microscopy
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- UniProt
- Q15019, Q14141, Q16181
- Ligands
- GDP, GTP, MG
Structure
electron microscopy · 6 distinct chains.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | — | protein | 234 | — | Q15019 |
| B | — | protein | 287 | — | Q14141 |
| C | — | protein | 270 | — | Q16181 |
| D | — | protein | 273 | — | Q16181 |
| E | — | protein | 296 | — | Q14141 |
| F | — | protein | 254 | — | Q15019 |
Ligands and binding sites
- GDP · Guanosine-5'-diphosphate · ligand · 4 copies · chains A, B, C, D, E, F
- GTP · Guanosine-5'-triphosphate · ligand · 2 copies · chains A, B, E, F
- MG · Magnesium ion · metal · chains E
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Compared structures
- 7M6J · Human Septin Hexameric Complex SEPT2G/SEPT6/SEPT7 by Single Particle Cryo-EM · the same entry in another collection · chain F against F, TM-score 1.00
- Q15019 · AlphaFold monomer V2.0 prediction for septin-2 (Q15019) · a predicted model of the same protein · chain F against A, TM-score 0.97
- Q14141 · AlphaFold monomer V2.0 prediction for septin-6 (Q14141) · a predicted model of the same protein · chain B against A, TM-score 0.96
- Q16181 · AlphaFold monomer V2.0 prediction for septin-7 (Q16181) · a predicted model of the same protein · chain D against A, TM-score 0.92
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q15019
- Every structure of UniProt Q14141
- Every structure of UniProt Q16181
- Elsewhere: RCSB PDB 7M6J · PDBe 7M6J · UniProt Q15019 · UniProt Q14141 · UniProt Q16181
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