UniProt Q15019
Septin-2 (Q15019)
Septin-2 (UniProt Q15019): 14 experimental structures and 1 predicted model on GenesisL1, 2 ligands bound, 21 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q15019
- Protein
- Septin-2
- Experimental structures
- 14
- Predicted models
- 1
- Ligands
- 2
- Pockets
- 21 · 4 records with a druggable one
Structures
15 records of Q15019 in the MolNFT archive: 14 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 2QA5 | Crystal structure of Sept2 G-domain | x-ray diffraction | A, B | — | — |
| 2QA5 | Crystal structure of SEPT2 G-domain | x-ray diffraction | A, B | — | — |
| 2QAG | Crystal structure of human septin trimer 2/6/7 | x-ray diffraction | A | — | — |
| 2QAG | Crystal structure of human septin trimer 2/6/7 | x-ray diffraction | A | — | — |
| 2QNR | Human septin 2 in complex with GDP | x-ray diffraction | A, B | — | — |
| 2QNR | Human septin 2 in complex with GDP | x-ray diffraction | A, B | — | — |
| 6UPA | Crystal Structure of GTPase Domain of Human Septin 2/Septin 6 Heterocomplex | x-ray diffraction | A | GTP, GDP | 3 (best 0.79) |
| 6UPA | Crystal structure of GTPase domain of human septin 2/SEPTIN 6 heterocomplex | x-ray diffraction | A | GTP, GDP | — |
| 6UPQ | Crystal Structure of GTPase Domain of Human Septin 2 / Septin 11 Heterocomplex | x-ray diffraction | A | GDP, GTP | — |
| 6UPQ | Crystal structure of GTPase domain of human septin 2 / septin 11 heterocomplex | x-ray diffraction | A | GDP, GTP | — |
| 6UPR | Crystal Structure of GTPase Domain of Human Septin 2 / Septin 8 Heterocomplex | x-ray diffraction | A | GDP, GTP | 5 (best 0.78) |
| 6UPR | Crystal structure of GTPase domain of human septin 2 / septin 8 heterocomplex | x-ray diffraction | A | GDP, GTP | — |
| 7M6J | Human Septin Hexameric Complex SEPT2G/SEPT6/SEPT7 by Single Particle Cryo-EM | electron microscopy | A, F | GDP, GTP | 10 (best 0.84) |
| 7M6J | Human septin hexameric complex SEPT2G/SEPT6/SEPT7 by single particle cryo-EM | electron microscopy | A, F | GDP, GTP | — |
| Q15019 | AlphaFold monomer V2.0 prediction for septin-2 (Q15019) | predicted | A | — | 3 (best 0.53) |
Ligands
Experiment against prediction
- 6UPQ chain A against the predicted model Q15019: TM-score 0.99, RMSD 0.64 Å
- 6UPQ chain A against the predicted model Q15019: TM-score 0.99, RMSD 0.64 Å
- 6UPA chain A against the predicted model Q15019: TM-score 0.99, RMSD 0.64 Å
- 6UPA chain A against the predicted model Q15019: TM-score 0.99, RMSD 0.64 Å
- 2QNR chain A against the predicted model Q15019: TM-score 0.99, RMSD 0.66 Å
- 2QNR chain A against the predicted model Q15019: TM-score 0.99, RMSD 0.66 Å
- 6UPR chain A against the predicted model Q15019: TM-score 0.98, RMSD 0.78 Å
- 6UPR chain A against the predicted model Q15019: TM-score 0.98, RMSD 0.78 Å
- 2QA5 chain A against the predicted model Q15019: TM-score 0.97, RMSD 1.06 Å
- 2QA5 chain A against the predicted model Q15019: TM-score 0.97, RMSD 1.06 Å
Elsewhere
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