MolNFT v1 · #178093 · protein

Cryo-EM structure of alpha-msh-bound melanocortin-1 receptor in complex with gs protein and NB35

7F4D: “Cryo-EM structure of alpha-msh-bound melanocortin-1 receptor in complex with gs protein and NB35”. Electron microscopy, 1 ligand (CA). MolNFT v1 #178093 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 7F4D
Type: protein
Length: 1,030 residues
Chains: 6
Method: electron microscopy
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
UniProt: P59768, P62873
Ligands: CA

Structure

electron microscopy · 6 distinct chains.

Chain	Molecule	Type	Residues	Secondary structure	UniProt
G	—	protein	56	—	P59768
A	—	protein	234	—	—
N	—	protein	127	—	—
B	—	protein	338	—	P62873
R	—	protein	263	—	—
M	—	protein	12	—	—

Ligands and binding sites

CA · Calcium ion · metal · chains R, M

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Compared structures

7F4D · Cryo-EM structure of alpha-MSH-bound melanocortin-1 receptor in complex with Gs protein… · the same entry in another collection · chain M against M, TM-score 1.00
P62873 · AlphaFold monomer V2.0 prediction for guanine nucleotide-binding protein G(I)/G(S)/G(T)… · a predicted model of the same protein · chain B against A, TM-score 0.99
P59768 · AlphaFold monomer V2.0 prediction for guanine nucleotide-binding protein G(I)/G(S)/G(O)… · a predicted model of the same protein · chain G against A, TM-score 0.93

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P59768
Every structure of UniProt P62873
Elsewhere: RCSB PDB 7F4D · PDBe 7F4D · UniProt P59768 · UniProt P62873

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