MolNFT v1 · #177788 · protein
Cryo-EM structure of SCAP/INSIG complex in the present of digitonin.
7ETW: “Cryo-EM structure of SCAP/INSIG complex in the present of digitonin.”. Electron microscopy, 2 ligands (AJP, NAG). MolNFT v1 #177788 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 7ETW
- Type
- protein
- Length
- 680 residues
- Chains
- 2
- Method
- electron microscopy
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- UniProt
- Q9Y5U4, Q12770
- Ligands
- AJP, NAG
Structure
electron microscopy · 2 distinct chains.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | — | protein | 197 | — | Q9Y5U4 |
| B | — | protein | 483 | — | Q12770 |
Ligands and binding sites
- AJP · Digitonin · ligand · 4 copies · chains A, B
- NAG · 2-acetamido-2-deoxy-beta-D-glucopyranose · sugar · 2 copies · chains B
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Compared structures
- 7ETW · Cryo-EM structure of Scap/Insig complex in the present of digitonin. · the same entry in another collection · chain A against A, TM-score 1.00
- Q9Y5U4 · AlphaFold monomer V2.0 prediction for insulin-induced gene 2 protein (Q9Y5U4) · a predicted model of the same protein · chain A against A, TM-score 0.85
- Q12770 · AlphaFold monomer V2.0 prediction for sterol regulatory element- binding protein… · a predicted model of the same protein · chain B against A, TM-score 0.52
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q9Y5U4
- Every structure of UniProt Q12770
- Elsewhere: RCSB PDB 7ETW · PDBe 7ETW · UniProt Q9Y5U4 · UniProt Q12770
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