MolNFT v1 · #177097 · protein
Crystal structure of enl yeats domain T1 mutant in complex with histone H3 acetylation at K27
7E7C · Protein enl: “Crystal structure of enl yeats domain T1 mutant in complex with histone H3 acetylation at K27”. X-ray diffraction, 1 ligand (IOD). MolNFT v1 #177097 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 7E7C
- Type
- protein
- Length
- 152 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Protein enl; Histone H3K27AC(24-27) peptide
- UniProt
- Q03111
- Ligands
- IOD
Structure
x-ray diffraction · 2 distinct chains · 8% helix, 49% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Protein enl | protein | 148 | 8% helix, 49% strand | Q03111 |
| B | Histone H3K27AC(24-27) peptide | protein | 4 | 0% helix, 25% strand | — |
Ligands and binding sites
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Interfaces
1 interface between chains.
- A–B · 375 Ų buried · 7 hydrogen bonds · protein-protein
Modifications
Observed in the structure: 1 modified (acetylation).
Compared structures
- 7E7C · Crystal structure of ENL YEATS domain T1 mutant in complex with histone H3 acetylation at… · the same entry in another collection · chain A against A, TM-score 1.00
- Q03111 · AlphaFold monomer V2.0 prediction for protein enl (Q03111) · a predicted model of the same protein · chain A against A, TM-score 0.93
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q03111
- Elsewhere: RCSB PDB 7E7C · PDBe 7E7C · UniProt Q03111
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