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MolNFT v1 · #176089 · protein

Human melatonin receptor MT1 - GI1 complex

7DB6: “Human melatonin receptor MT1 - GI1 complex”. Electron microscopy, 1 ligand (JEV). MolNFT v1 #176089 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB
7DB6
Type
protein
Length
1,116 residues
Chains
5
Method
electron microscopy
Collection
MolNFT v1 / PDB
Contract
0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner
0x3396CDB397284571d12822B4ae1189a8E22AAAAA
UniProt
P63096, P63212, P48039
Ligands
JEV

Structure

electron microscopy · 5 distinct chains.

ChainMoleculeTypeResiduesSecondary structureUniProt
A—protein219—P63096
B—protein336——
C—protein53—P63212
E—protein232——
D—protein276—P48039

Ligands and binding sites

  • JEV · N-{2-[(8S)-1,6,7,8-tetrahydro-2H-indeno[5,4-b]furan-8-yl]ethyl}propanamide · ligand · chains D

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Compared structures

  • 7DB6 · human melatonin receptor MT1 - Gi1 complex · the same entry in another collection · chain D against D, TM-score 1.00
  • P48039 · AlphaFold monomer V2.0 prediction for melatonin receptor type 1A (P48039) · a predicted model of the same protein · chain D against A, TM-score 0.92
  • P63096 · AlphaFold monomer V2.0 prediction for guanine nucleotide-binding protein G(I) subunit… · a predicted model of the same protein · chain A against A, TM-score 0.78
  • P63212 · AlphaFold monomer V2.0 prediction for guanine nucleotide-binding protein G(I)/G(S)/G(O)… · a predicted model of the same protein · chain C against A, TM-score 0.64

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