MolNFT v1 · #175453 · protein
Human KCNQ2-cam in complex with retigabine
7CR7: “Human KCNQ2-cam in complex with retigabine”. Electron microscopy, 1 ligand (FBX). MolNFT v1 #175453 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 7CR7
- Type
- protein
- Length
- 1,988 residues
- Chains
- 8
- Method
- electron microscopy
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- UniProt
- O43526, P0DP25
- Ligands
- FBX
Structure
electron microscopy · 2 distinct chains.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, B, D, G | — | protein | 354 | — | O43526 |
| F, C, E, H | — | protein | 143 | — | P0DP25 |
Ligands and binding sites
- FBX · Ethyl N-[2-azanyl-4-[(4-fluorophenyl) methylamino]phenyl]carbamate · ligand · 4 copies · chains A, G, B, D
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Compared structures
- 7CR7 · human KCNQ2-CaM in complex with retigabine · the same entry in another collection · chain H against H, TM-score 1.00
- O43526 · AlphaFold monomer V2.0 prediction for potassium voltage-gated channel subfamily kqt… · a predicted model of the same protein · chain A against A, TM-score 0.76
- P0DP25 · AlphaFold monomer V2.0 prediction for calmodulin-3 (P0DP25) · a predicted model of the same protein · chain E against A, TM-score 0.55
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt O43526
- Every structure of UniProt P0DP25
- Elsewhere: RCSB PDB 7CR7 · PDBe 7CR7 · UniProt O43526 · UniProt P0DP25
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