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Ligand · FBX

FBX · Ethyl N-[2-azanyl-4-[(4-fluorophenyl) methylamino]phenyl]carbamate

FBX, Ethyl N-[2-azanyl-4-[(4-fluorophenyl) methylamino]phenyl]carbamate (C16 H18 F N3 O2, 303.3 g/mol), in the MolNFT structures on GenesisL1: bound in 3 records (3 PDB entries). Every binding site with its residues within 4.5 Å, the…

Component
FBX
Formula
C16 H18 F N3 O2
Class
ligand
Structures
3
PDB entries
3

Binding sites

FBX in 3 structures; the first of them:

  • 7BYM · Cryo-EM structure of human KCNQ4 with retigabine · FBX A702 · binds LEU305, SER309, PHE110, TRP242, PHE246, LEU249, PHE311, LEU318
  • 7CR2 · Human KCNQ2 in complex with retigabine · FBX A801 · binds TRP236, PHE240, LEU243, PHE305, PRO308, LEU299, ILE300, SER303
  • 7CR7 · Human KCNQ2-cam in complex with retigabine · FBX A1001 · binds TRP236, PHE240, PHE305, PRO308, LEU299, ILE300, SER303, PHE304

Residues it binds most

PHE 12, LEU 12, SER 12, TRP 12, PRO 10, ILE 8 (residue and the binding sites it lines).

Found with

  • PT5 · (1S)-2-{[(R)-hydroxy{[(1r,2r,3s,4r,5r,6s)-2,3,6-trihydroxy-4,5-bis(phosphonooxy) cyclohexyl]oxy}phosphoryl]oxy}-1-[(octadecanoyloxy) methyl]ethyl (8E,11E)-icosa-5,8,11,14-tetraenoate
  • K · Potassium ion

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