UniProt O43526
Potassium voltage-gated channel subfamily KQT member 2 (O43526)
Potassium voltage-gated channel subfamily KQT member 2 (UniProt O43526): 15 experimental structures on GenesisL1, 5 ligands bound, 56 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.
- UniProt
- O43526
- Protein
- Potassium voltage-gated channel subfamily KQT member 2
- Experimental structures
- 15
- Predicted models
- 0
- Ligands
- 5
- Pockets
- 56 · 3 records with a druggable one
Structures
15 records of O43526 in the MolNFT archive: 15 experimental, 0 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 5J03 | Crystal Structure of a chimeric Kv7.2 - Kv7.3 proximal C-terminal Domain in Complex with Calmodulin | x-ray diffraction | A | — | — |
| 5J03 | Crystal structure of a chimeric KV7.2 - KV7.3 proximal C-terminal domain in complex with calmodulin | x-ray diffraction | A | — | — |
| 6FEG | Solution structure of CAM/KV7.2-hab complex | solution nmr | A | — | — |
| 6FEH | Solution structure of CAM/KV7.2-hab complex | solution nmr | A | — | — |
| 7CR0 | human KCNQ2 in apo state | electron microscopy | A, B, C, D | — | 16 (best 0.84) |
| 7CR0 | Human KCNQ2 in apo state | electron microscopy | A, B, C, D | — | — |
| 7CR1 | human KCNQ2 in complex with ztz240 | electron microscopy | A, B, C, D | GB9 | — |
| 7CR1 | Human KCNQ2 in complex with ZTZ240 | electron microscopy | A, B, C, D | GB9 | — |
| 7CR2 | Human KCNQ2 in complex with retigabine | electron microscopy | A, B, C, D | FBX | — |
| 7CR3 | Human KCNQ2-cam in apo state | — | — | — | |
| 7CR4 | Human KCNQ2-cam in complex with ZTZ240 | electron microscopy | A, B, D, F | GB9 | — |
| 7CR7 | Human KCNQ2-cam in complex with retigabine | electron microscopy | A, B, D, G | FBX | — |
| 8J01 | Human KCNQ2-CaM in complex with CBD and PIP2 | electron microscopy | A, B, D, G | P0T, PIO | 20 (best 0.85) |
| 8J04 | Human KCNQ2-CaM-HN37 complex in the presence of PIP2 | electron microscopy | A, B, D, G | 9MF | 20 (best 0.85) |
| O43526 | AlphaFold monomer V2.0 prediction for potassium voltage-gated channel subfamily kqt member 2… | — | — | — |
Ligands
- GB9 · N-(6-chloranylpyridin-3-yl)-4-fluoranyl-benzamide · in 3 records
- FBX · Ethyl N-[2-azanyl-4-[(4-fluorophenyl) methylamino]phenyl]carbamate · in 2 records
- 9MF · methyl N-[4-[(4-fluorophenyl)methyl-prop-2-ynyl-amino]-2,6-dimethyl-phenyl]carbamate · in 1 record
- P0T · cannabidiol · in 1 record
- PIO · [(2R)-2-octanoyloxy-3-[oxidanyl-[(1R,2R,3S,4R,5R,6S)-2, 3,6-tris(oxidanyl)-4,5-diphosphonooxy-cyclohexyl]oxy-phosphoryl]oxy-propyl] octanoate · in 1 record
Elsewhere
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