MolNFT v1 · #174699 · protein

Human mdmx protein in complex with NUTLIN3A

7C3Q: “Human mdmx protein in complex with NUTLIN3A”. X-ray diffraction, 2 ligands (O4B, NUT). MolNFT v1 #174699 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 7C3Q
Type: protein
Length: 96 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
UniProt: O15151
Ligands: O4B, NUT

Structure

x-ray diffraction · 1 distinct chain.

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	—	protein	96	—	O15151

Ligands and binding sites

O4B · 1,4,7,10,13,16-hexaoxacyclooctadecane · ligand · chains A
NUT · 4-({(4S,5R)-4,5-bis(4-chlorophenyl)-2-[4-methoxy-2-(propan-2-yloxy)phenyl]-4,5-dihydro-1H-imidazol-1-yl}carbonyl)piperazin-2-one · ligand · chains A
PEG · Di(hydroxyethyl)ether · additive · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Compared structures

7C3Q · Human MdmX protein in complex with Nutlin3a · the same entry in another collection · chain A against A, TM-score 1.00
O15151 · AlphaFold monomer V2.0 prediction for protein MDM4 (O15151) · a predicted model of the same protein · chain A against A, TM-score 0.89

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt O15151
Elsewhere: RCSB PDB 7C3Q · PDBe 7C3Q · UniProt O15151

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