Cryo-EM structure of the formoterol-bound BETA2 adrenergic receptor-gs protein complex.

Structure

electron microscopy · 5 distinct chains.

Ligands and binding sites

• H98 · ~{N}-[5-[(1~{R})-2-[[(2~{R})-1-(4-methoxyphenyl)propan-2-yl]amino]-1-oxidanyl-ethyl]-2-oxidanyl-phenyl]methanamide · ligand · chains R

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Compared structures

• 7BZ2 · Cryo-EM structure of the formoterol-bound beta2 adrenergic receptor-Gs protein complex. · the same entry in another collection · chain B against B, TM-score 1.00
• P62871 · AlphaFold monomer V2.0 prediction for guanine nucleotide-binding protein G(I)/G(S)/G(T)… · a predicted model of the same protein · chain B against A, TM-score 0.99
• P63212 · AlphaFold monomer V2.0 prediction for guanine nucleotide-binding protein G(I)/G(S)/G(O)… · a predicted model of the same protein · chain G against A, TM-score 0.61

Analyse

• Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
• Every structure of UniProt P63092
• Every structure of UniProt P62871
• Every structure of UniProt P63212
• Elsewhere: RCSB PDB 7BZ2 · PDBe 7BZ2 · UniProt P63092 · UniProt P62871 · UniProt P63212