Crystal structure of an engineered helicase domain construct for human bloom syndrome protein (blm)

Structure

x-ray diffraction · 1 distinct chain.

Ligands and binding sites

• ADP · Adenosine-5'-diphosphate · ligand · chains A
• MG · Magnesium ion · metal · 2 copies · chains A
• CA · Calcium ion · metal · 2 copies · chains A
• ZN · Zinc ion · metal · chains A
• EDO · 1,2-ethanediol · additive · 6 copies · chains A
• ACT · Acetate ion · additive · 4 copies · chains A
• PG4 · Tetraethylene glycol · additive · 2 copies · chains A
• GOL · Glycerol · additive · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Compared structures

• 7AUC · Crystal structure of an engineered helicase domain construct for human Bloom syndrome… · the same entry in another collection · chain A against A, TM-score 1.00
• P54132 · AlphaFold monomer V2.0 prediction for bloom syndrome protein (P54132) · a predicted model of the same protein · chain A against A, TM-score 0.94

Analyse

• Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
• Every structure of UniProt P54132
• Elsewhere: RCSB PDB 7AUC · PDBe 7AUC · UniProt P54132