MolNFT v1 · #173045 · protein
RET/GDNF/GFRA1 extracellular complex cryo-EM structure
7AML: “RET/GDNF/GFRA1 extracellular complex cryo-EM structure”. Electron microscopy, 2 ligands (NAG, CA). MolNFT v1 #173045 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 7AML
- Type
- protein
- Length
- 1,996 residues
- Chains
- 6
- Method
- electron microscopy
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- UniProt
- A8E7C6, Q98TT9, Q98TU0
- Ligands
- NAG, CA
Structure
electron microscopy · 3 distinct chains.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, D | — | protein | 596 | — | A8E7C6 |
| B, E | — | protein | 304 | — | Q98TT9 |
| C, F | — | protein | 98 | — | Q98TU0 |
Ligands and binding sites
- NAG · 2-acetamido-2-deoxy-beta-D-glucopyranose · sugar · 16 copies · chains A, D, C, F
- CA · Calcium ion · metal · 8 copies · chains A, D
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Compared structures
- 7AML · RET/GDNF/GFRa1 extracellular complex Cryo-EM structure · the same entry in another collection · chain F against F, TM-score 1.00
- Q98TU0 · AlphaFold monomer V2.0 prediction for glial cell line-derived neurotrophic factor (Q98TU0) · a predicted model of the same protein · chain C against A, TM-score 0.91
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt A8E7C6
- Every structure of UniProt Q98TT9
- Every structure of UniProt Q98TU0
- Elsewhere: RCSB PDB 7AML · PDBe 7AML · UniProt A8E7C6 · UniProt Q98TT9 · UniProt Q98TU0
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