UniProt Q98TU0
Glial cell line-derived neurotrophic factor (Q98TU0)
Glial cell line-derived neurotrophic factor (UniProt Q98TU0): 5 experimental structures and 1 predicted model on GenesisL1, 1 ligand bound, 6 pockets. Binding sites, druggability and experiment against prediction (TM-score) in…
- UniProt
- Q98TU0
- Protein
- Glial cell line-derived neurotrophic factor
- Experimental structures
- 5
- Predicted models
- 1
- Ligands
- 1
- Pockets
- 6 · 1 record with a druggable one
Structures
6 records of Q98TU0 in the MolNFT archive: 5 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 7AB8 | Crystal structure of a GDNF-GFRalpha1 complex | x-ray diffraction | B | NAG | — |
| 7AB8 | Crystal structure of a gdnf-GFRALPHA1 complex | x-ray diffraction | B | NAG | — |
| 7AML | RET/GDNF/GFRa1 extracellular complex Cryo-EM structure | electron microscopy | C, F | NAG | 6 (best 0.70) |
| 7AML | RET/GDNF/GFRA1 extracellular complex cryo-EM structure | electron microscopy | C, F | NAG | — |
| 8OS6 | Structure of a GFRA1/GDNF LICAM complex | x-ray diffraction | B, D, F, H, J, L, N, P, R, T | NAG | — |
| Q98TU0 | AlphaFold monomer V2.0 prediction for glial cell line-derived neurotrophic factor (Q98TU0) | predicted | A | — | — |
Ligands
- NAG · 2-acetamido-2-deoxy-beta-D-glucopyranose · in 5 records
Experiment against prediction
- 8OS6 chain T against the predicted model Q98TU0: TM-score 0.97, RMSD 0.58 Å
- 8OS6 chain P against the predicted model Q98TU0: TM-score 0.97, RMSD 0.60 Å
- 8OS6 chain N against the predicted model Q98TU0: TM-score 0.97, RMSD 0.62 Å
- 8OS6 chain R against the predicted model Q98TU0: TM-score 0.97, RMSD 0.66 Å
- 8OS6 chain H against the predicted model Q98TU0: TM-score 0.96, RMSD 0.92 Å
- 8OS6 chain L against the predicted model Q98TU0: TM-score 0.96, RMSD 0.92 Å
- 8OS6 chain B against the predicted model Q98TU0: TM-score 0.96, RMSD 1.26 Å
- 7AB8 chain B against the predicted model Q98TU0: TM-score 0.96, RMSD 1.48 Å
- 7AB8 chain B against the predicted model Q98TU0: TM-score 0.96, RMSD 1.48 Å
- 8OS6 chain J against the predicted model Q98TU0: TM-score 0.95, RMSD 1.46 Å
Elsewhere
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