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UniProt A8E7C6

Proto-oncogene tyrosine-protein kinase receptor Ret (A8E7C6)

Proto-oncogene tyrosine-protein kinase receptor Ret (UniProt A8E7C6), EC 2.7.10.1: 4 experimental structures on GenesisL1, 4 ligands bound, 22 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.

UniProt
A8E7C6
Protein
Proto-oncogene tyrosine-protein kinase receptor Ret
EC
2.7.10.1
Experimental structures
4
Predicted models
0
Ligands
4
Pockets
22 · 2 records with a druggable one

Structures

4 records of A8E7C6 in the MolNFT archive: 4 experimental, 0 predicted.

EntryTitleMethodChainsLigandsPockets
7AMKZebrafish RET Cadherin Like Domains 1 to 4.x-ray diffractionA, BNAG, FUC, MAN, CA8 (best 0.78)
7AMKZebrafish ret cadherin like domains 1 to 4.x-ray diffractionA, BNAG, FUC, MAN, CA—
7AMLRET/GDNF/GFRa1 extracellular complex Cryo-EM structureelectron microscopyA, DCA, NAG14 (best 0.78)
7AMLRET/GDNF/GFRA1 extracellular complex cryo-EM structureelectron microscopyA, DCA, NAG—

Ligands

  • CA · Calcium ion · in 4 records
  • NAG · 2-acetamido-2-deoxy-beta-D-glucopyranose · in 4 records
  • FUC · alpha-L-fucopyranose · in 2 records
  • MAN · alpha-D-mannopyranose · in 2 records

Elsewhere

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