MolNFT v1 · #172385 · protein
Structure of dimeric sodium proton antiporter nhaa K300R variant, at pH 8.2, crystallized with chimeric Fab antibodies
7A0Y: “Structure of dimeric sodium proton antiporter nhaa K300R variant, at pH 8.2, crystallized with chimeric Fab…”. X-ray diffraction, 5 ligands (3PH, CDL, 3PE). MolNFT v1 #172385 on GenesisL1: 3D structure, binding sites and pockets in…
- PDB
- 7A0Y
- Type
- protein
- Length
- 1,597 residues
- Chains
- 6
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- UniProt
- Q8ZRZ3
- Ligands
- 3PH, CDL, 3PE, CL, PO4
Structure
x-ray diffraction · 6 distinct chains.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | — | protein | 372 | — | Q8ZRZ3 |
| B | — | protein | 373 | — | Q8ZRZ3 |
| C | — | protein | 213 | — | — |
| D | — | protein | 207 | — | — |
| E | — | protein | 223 | — | — |
| F | — | protein | 209 | — | — |
Ligands and binding sites
- 3PH · 1,2-diacyl-glycerol-3-sn-phosphate · ligand · 3 copies · chains A, B
- CDL · Cardiolipin · ligand · chains A, B
- 3PE · 1,2-diacyl-sn-glycero-3-phosphoethanolamine · ligand · chains A, B
- CL · Chloride ion · ion · 4 copies · chains C, D, E, F
- PO4 · Phosphate ion · ion · 2 copies · chains A, B
- PG4 · Tetraethylene glycol · additive · 2 copies · chains A, D, B, F
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Compared structures
- 7A0Y · Structure of dimeric sodium proton antiporter NhaA K300R variant, at pH 8.2, crystallized… · the same entry in another collection · chain F against F, TM-score 1.00
- Q8ZRZ3 · AlphaFold monomer V2.0 prediction for NA(+)/H(+) antiporter nhaa (Q8ZRZ3) · a predicted model of the same protein · chain A against A, TM-score 0.98
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q8ZRZ3
- Elsewhere: RCSB PDB 7A0Y · PDBe 7A0Y · UniProt Q8ZRZ3
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.