Research workbench
Structure of dimeric sodium proton antiporter nhaa K300R variant, at pH 8.2, crystallized with chimeric Fab antibodies
Analyse Structure of dimeric sodium proton antiporter nhaa K300R variant, at pH 8.2… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 7A0Y
- Type
- protein
- Length
- 1,597 residues
- Chains
- 6
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- UniProt
- Q8ZRZ3
- Ligands
- 3PH, CDL, 3PE, CL, PO4
Structure
x-ray diffraction · 6 distinct chains.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | — | protein | 372 | — | Q8ZRZ3 |
| B | — | protein | 373 | — | Q8ZRZ3 |
| C | — | protein | 213 | — | — |
| D | — | protein | 207 | — | — |
| E | — | protein | 223 | — | — |
| F | — | protein | 209 | — | — |
Ligands and binding sites
- 3PH · 1,2-diacyl-glycerol-3-sn-phosphate · ligand · 3 copies · chains A, B
- CDL · Cardiolipin · ligand · chains A, B
- 3PE · 1,2-diacyl-sn-glycero-3-phosphoethanolamine · ligand · chains A, B
- CL · Chloride ion · ion · 4 copies · chains C, D, E, F
- PO4 · Phosphate ion · ion · 2 copies · chains A, B
- PG4 · Tetraethylene glycol · additive · 2 copies · chains A, D, B, F
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Compared structures
- 7A0Y · Structure of dimeric sodium proton antiporter NhaA K300R variant, at pH 8.2, crystallized… · the same entry in another collection · chain F against F, TM-score 1.00
- Q8ZRZ3 · AlphaFold monomer V2.0 prediction for NA(+)/H(+) antiporter nhaa (Q8ZRZ3) · a predicted model of the same protein · chain A against A, TM-score 0.98
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q8ZRZ3
- Elsewhere: RCSB PDB 7A0Y · PDBe 7A0Y · UniProt Q8ZRZ3
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