MolNFT v1 · #172384 · protein
Structure of dimeric sodium proton antiporter nhaa, at pH 6.0, crystallized with chimeric Fab antibodies
7A0X: “Structure of dimeric sodium proton antiporter nhaa, at pH 6.0, crystallized with chimeric Fab antibodies”. X-ray diffraction, 6 ligands (3PH, CDL, 3PE). MolNFT v1 #172384 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 7A0X
- Type
- protein
- Length
- 1,592 residues
- Chains
- 6
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- UniProt
- Q8ZRZ3
- Ligands
- 3PH, CDL, 3PE, CA, CL, PO4
Structure
x-ray diffraction · 6 distinct chains.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | — | protein | 370 | — | Q8ZRZ3 |
| B | — | protein | 373 | — | Q8ZRZ3 |
| C | — | protein | 210 | — | — |
| D | — | protein | 207 | — | — |
| E | — | protein | 223 | — | — |
| F | — | protein | 209 | — | — |
Ligands and binding sites
- 3PH · 1,2-diacyl-glycerol-3-sn-phosphate · ligand · 3 copies · chains A, B
- CDL · Cardiolipin · ligand · chains A, B
- 3PE · 1,2-diacyl-sn-glycero-3-phosphoethanolamine · ligand · chains B
- CA · Calcium ion · metal · chains F
- CL · Chloride ion · ion · 3 copies · chains C, E, F
- PO4 · Phosphate ion · ion · 2 copies · chains A, B
- PG4 · Tetraethylene glycol · additive · 4 copies · chains A, D, B, F, E
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Compared structures
- 7A0X · Structure of dimeric sodium proton antiporter NhaA, at pH 6.0, crystallized with chimeric… · the same entry in another collection · chain F against F, TM-score 1.00
- Q8ZRZ3 · AlphaFold monomer V2.0 prediction for NA(+)/H(+) antiporter nhaa (Q8ZRZ3) · a predicted model of the same protein · chain A against A, TM-score 0.98
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q8ZRZ3
- Elsewhere: RCSB PDB 7A0X · PDBe 7A0X · UniProt Q8ZRZ3
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