MolNFT v1 · #171398 · protein
Repulsive guidance molecule a (rgma) in complex with growth differentiation factor 5 (GDF5)
6Z3G · GROWTH/DIFFERENTIATION factor 5: “Repulsive guidance molecule a (rgma) in complex with growth differentiation factor 5 (GDF5)”. X-ray diffraction. MolNFT v1 #171398 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 6Z3G
- Type
- protein
- Length
- 162 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- GROWTH/DIFFERENTIATION factor 5; Repulsive guidance molecule a
- UniProt
- P43026, Q96B86
Structure
x-ray diffraction · 2 distinct chains · 31% helix, 29% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | GROWTH/DIFFERENTIATION factor 5 | protein | 105 | 20% helix, 45% strand | P43026 |
| B | Repulsive guidance molecule a | protein | 57 | 53% helix, 0% strand | Q96B86 |
Ligands and binding sites
- CIT · Citric acid · additive · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Interfaces
1 interface between chains.
- A–B · 411 Ų buried · 3 hydrogen bonds · protein-protein
Modifications
Observed in the structure: 6 disulfide (disulfide).
Compared structures
- 6Z3G · Repulsive Guidance Molecule A (RGMA) in complex with Growth Differentiation Factor 5… · the same entry in another collection · chain A against A, TM-score 1.00
- P43026 · AlphaFold monomer V2.0 prediction for GROWTH/DIFFERENTIATION factor 5 (P43026) · a predicted model of the same protein · chain A against A, TM-score 0.95
- Q96B86 · AlphaFold monomer V2.0 prediction for repulsive guidance molecule a (Q96B86) · a predicted model of the same protein · chain B against A, TM-score 0.91
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P43026
- Every structure of UniProt Q96B86
- Elsewhere: RCSB PDB 6Z3G · PDBe 6Z3G · UniProt P43026 · UniProt Q96B86
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