MolNFT v1 · #341579 · protein

AlphaFold monomer V2.0 prediction for repulsive guidance molecule a (Q96B86)

Q96B86: “AlphaFold monomer V2.0 prediction for repulsive guidance molecule a (Q96B86)”. 6 pockets (best druggability 0.58). MolNFT v1 #341579 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

Accession: Q96B86
Type: protein
Length: 450 residues
Chains: 1
Collection: MolNFT v1 / AlphaFold
Contract: 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
Owner: 0x7c75F0f7d6d136A2b8D4C6C6e9b3D8a697949DF1
Molecule: Repulsive guidance molecule a
UniProt: Q96B86
Pockets: 6 · best druggability 0.58

Structure

1 distinct chain · 30% helix, 18% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Repulsive guidance molecule a	protein	450	30% helix, 18% strand	Q96B86

Pockets

6 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	356	0.58	0.76	40	empty
2	145	0.46	0.77	19	empty
3	103	0.34	0.73	28	empty
4	57	0.30	0.76	15	empty
5	67	0.29	0.74	16	empty

Modifications

Observed in the structure: 7 disulfide (disulfide).

Compared structures

4UHY · Crystal structure of the human RGMA-BMP2 complex · an experimental structure of the same protein · chain A against C, TM-score 0.14
4UHY · Crystal structure of the human rgma-BMP2 complex · an experimental structure of the same protein · chain A against C, TM-score 0.14
6Z3G · Repulsive guidance molecule a (rgma) in complex with growth differentiation factor 5… · an experimental structure of the same protein · chain A against B, TM-score 0.13

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q96B86
Elsewhere: UniProt Q96B86 · AlphaFold DB Q96B86

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