Research workbench
AlphaFold monomer V2.0 prediction for repulsive guidance molecule a (Q96B86)
Analyse AlphaFold monomer V2.0 prediction for repulsive guidance molecule a (Q96B86) in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- Accession
- Q96B86
- Type
- protein
- Length
- 450 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x7c75F0f7d6d136A2b8D4C6C6e9b3D8a697949DF1
- Molecule
- Repulsive guidance molecule a
- UniProt
- Q96B86
- Pockets
- 6 · best druggability 0.58
Structure
1 distinct chain · 30% helix, 18% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Repulsive guidance molecule a | protein | 450 | 30% helix, 18% strand | Q96B86 |
Pockets
6 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 356 | 0.58 | 0.76 | 40 | empty |
| 2 | 145 | 0.46 | 0.77 | 19 | empty |
| 3 | 103 | 0.34 | 0.73 | 28 | empty |
| 4 | 57 | 0.30 | 0.76 | 15 | empty |
| 5 | 67 | 0.29 | 0.74 | 16 | empty |
Modifications
Observed in the structure: 7 disulfide (disulfide).
Compared structures
- 4UHY · Crystal structure of the human RGMA-BMP2 complex · an experimental structure of the same protein · chain A against C, TM-score 0.14
- 4UHY · Crystal structure of the human rgma-BMP2 complex · an experimental structure of the same protein · chain A against C, TM-score 0.14
- 6Z3G · Repulsive guidance molecule a (rgma) in complex with growth differentiation factor 5… · an experimental structure of the same protein · chain A against B, TM-score 0.13
- 6Z3G · Repulsive Guidance Molecule A (RGMA) in complex with Growth Differentiation Factor 5… · an experimental structure of the same protein · chain A against B, TM-score 0.13
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q96B86
- Elsewhere: UniProt Q96B86 · AlphaFold DB Q96B86
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