MolNFT v1 · #171187 · protein
NMR solution structure of unbound recombinant human nerve growth factor (rhngf)
6YW8 · Beta-nerve growth factor: “NMR solution structure of unbound recombinant human nerve growth factor (rhngf)”. Solution nmr, 1 pocket (best druggability 0.59). MolNFT v1 #171187 on GenesisL1: 3D structure, binding sites and pockets in…
- PDB
- 6YW8
- Type
- protein
- Length
- 236 residues
- Chains
- 2
- Method
- solution nmr
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Beta-nerve growth factor
- UniProt
- P01138
- Pockets
- 1 · best druggability 0.59
Structure
solution nmr · 1 distinct chain · 0% helix, 53% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, B | Beta-nerve growth factor | protein | 118 | 0% helix, 53% strand | P01138 |
Pockets
1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 375 | 0.59 | 0.76 | 41 | empty |
Interfaces
1 interface between chains.
- A–B · 1948 Ų buried · 16 hydrogen bonds · protein-protein
Modifications
Observed in the structure: 6 disulfide (disulfide).
Compared structures
- 6YW8 · NMR solution structure of unbound recombinant human Nerve Growth Factor (rhNGF) · the same entry in another collection · chain A against A, TM-score 1.00
- P01138 · AlphaFold monomer V2.0 prediction for beta-nerve growth factor (P01138) · a predicted model of the same protein · chain A against A, TM-score 0.68
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P01138
- Elsewhere: RCSB PDB 6YW8 · PDBe 6YW8 · UniProt P01138
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.