UniProt P01138
Beta-nerve growth factor (P01138)
Beta-nerve growth factor (UniProt P01138): 15 experimental structures and 1 predicted model on GenesisL1, 21 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P01138
- Protein
- Beta-nerve growth factor
- Experimental structures
- 15
- Predicted models
- 1
- Pockets
- 21 · 3 records with a druggable one
Structures
16 records of P01138 in the MolNFT archive: 15 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1SG1 | Crystal Structure of the Receptor-Ligand Complex between Nerve Growth Factor and the Common… | x-ray diffraction | A, B | — | — |
| 1SG1 | Crystal structure of the receptor-ligand complex between nerve growth factor and the common… | x-ray diffraction | A, B | — | — |
| 1WWW | Ngf in complex with domain 5 of the trka receptor | x-ray diffraction | V, W | — | — |
| 1WWW | Ngf in complex with domain 5 of the trka receptor | x-ray diffraction | V, W | — | — |
| 2IFG | Structure of the extracellular segment of human TRKA in complex with nerve growth factor | x-ray diffraction | E, F | — | — |
| 2IFG | Structure of the extracellular segment of human trka in complex with nerve growth factor | x-ray diffraction | E, F | — | — |
| 4EDW | Nerve Growth Factor in Complex with Fab from humanized version of mouse mAb 911 (tanezumab) | x-ray diffraction | V | — | — |
| 4EDW | Nerve growth factor in complex with Fab from humanized version of mouse mab 911 (tanezumab) | x-ray diffraction | V | — | — |
| 4EDX | Nerve Growth Factor in Complex with Fab from mouse mAb 911 | x-ray diffraction | W, V | — | — |
| 4EDX | Nerve growth factor in complex with Fab from mouse mab 911 | x-ray diffraction | W, V | — | — |
| 4ZBN | Non-helical DNA Triplex Forms a Unique Aptamer Scaffold for High Affinity Recognition of Nerve… | x-ray diffraction | A, B | — | 5 (best 0.75) |
| 4ZBN | Non-helical DNA triplex forms a unique aptamer scaffold for high affinity recognition of nerve… | x-ray diffraction | A, B | — | — |
| 5JZ7 | NGF IN COMPLEX WITH MEDI578 scFv | x-ray diffraction | A, B, E, F | — | 14 (best 0.78) |
| 5JZ7 | Ngf in complex with MEDI578 scfv | x-ray diffraction | A, B, E, F | — | — |
| 6YW8 | NMR solution structure of unbound recombinant human nerve growth factor (rhngf) | solution nmr | A, B | — | — |
| P01138 | AlphaFold monomer V2.0 prediction for beta-nerve growth factor (P01138) | predicted | A | — | 2 (best 0.54) |
Experiment against prediction
- 4EDX chain V against the predicted model P01138: TM-score 0.90, RMSD 1.59 Å
- 4EDX chain V against the predicted model P01138: TM-score 0.90, RMSD 1.59 Å
- 4EDX chain W against the predicted model P01138: TM-score 0.90, RMSD 1.59 Å
- 4EDX chain W against the predicted model P01138: TM-score 0.90, RMSD 1.59 Å
- 1SG1 chain A against the predicted model P01138: TM-score 0.89, RMSD 1.44 Å
- 1SG1 chain A against the predicted model P01138: TM-score 0.89, RMSD 1.44 Å
- 4ZBN chain A against the predicted model P01138: TM-score 0.88, RMSD 1.77 Å
- 4ZBN chain A against the predicted model P01138: TM-score 0.88, RMSD 1.77 Å
- 5JZ7 chain F against the predicted model P01138: TM-score 0.88, RMSD 1.63 Å
- 5JZ7 chain B against the predicted model P01138: TM-score 0.87, RMSD 2.12 Å
Elsewhere
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