MolNFT v1 · #171184 · protein
Hif prolyl hydroxylase 2 (PHD2/ EGLN1) in complex with N-oxalylglycine (nog) and a rapid-derived silent allosteric cyclic peptide 3C (14- mer)
6YW4: “Hif prolyl hydroxylase 2 (PHD2/ EGLN1) in complex with N-oxalylglycine (nog) and a rapid-derived silent…”. X-ray diffraction, 4 ligands (48V, OGA, MN). MolNFT v1 #171184 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 6YW4
- Type
- protein
- Length
- 223 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- UniProt
- Q9GZT9
- Ligands
- 48V, OGA, MN, SO4
Structure
x-ray diffraction · 2 distinct chains.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | — | protein | 210 | — | Q9GZT9 |
| B | — | protein | 13 | — | — |
Ligands and binding sites
- 48V · {[(2R)-2,3-diamino-3-oxopropyl]sulfanyl}acetic acid · ligand · chains B
- OGA · N-oxalylglycine · ligand · chains A
- MN · Manganese (II) ion · metal · chains A
- SO4 · Sulfate ion · ion · 2 copies · chains A, B
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Compared structures
- 6YW4 · HIF prolyl hydroxylase 2 (PHD2/ EGLN1) in complex with N-oxalylglycine (NOG) and a… · the same entry in another collection · chain A against A, TM-score 1.00
- Q9GZT9 · AlphaFold monomer V2.0 prediction for egl nine homolog 1 (Q9GZT9) · a predicted model of the same protein · chain A against A, TM-score 0.98
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q9GZT9
- Elsewhere: RCSB PDB 6YW4 · PDBe 6YW4 · UniProt Q9GZT9
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