Ligand · 48V
48V · {[(2R)-2,3-diamino-3-oxopropyl]sulfanyl}acetic acid
48V, {[(2R)-2,3-diamino-3-oxopropyl]sulfanyl}acetic acid (C5 H10 N2 O3 S, 178.2 g/mol), in the MolNFT structures on GenesisL1: bound in 16 records (16 PDB entries). Every binding site with its residues within 4.5 Å, the residues it binds…
- Component
- 48V
- Formula
- C5 H10 N2 O3 S
- Class
- ligand
- Structures
- 16
- PDB entries
- 16
Binding sites
48V in 16 structures; the first of them:
- 5LY1 · JMJD2A/ KDM4A complexed with NI(II) and macrocyclic peptide inhibitor CP2 (13-mer) · 48V E0 · binds GLN88, DTY1, TYR12, THR13
- 5LY2 · JMJD2A/ KDM4A complexed with NI(II), nog and macrocyclic peptide inhibitor CP2_R6KME3… · 48V E0 · binds GLN88, DTY1, TYR12, THR13, TYR3
- 5TYI · GRB7 SH2 with bicyclic peptide containing py mimetic · 48V L9 · binds ASP496, ASP497, GLN499, LYS478, LYS1, PHE2, ASN7, GLU8 and 2 more
- 5U06 · GRB7-SH2 with bicyclic peptide inhibitor containing a py mimetic · 48V L9 · binds ASP496, ASP497, LYS1, PHE2, ASN7, GLU8, GLU8
- 5U1Q · GRB7-SH2 with bicyclic peptide inhibitor · 48V L9 · binds ASP496, GLN499, LYS1, ASN7, GLU8
- 6B67 · Human PP2CALPHA (PPM1A) complexed with cyclic peptide C(MPSIPYVA) · 48V D7 · binds ARG186, ARG281, MET1, PTR4, VAL5, ALA6
- 6XS5 · Crystal structure of human VPS29 complexed with rapid-derived cyclic peptide rt-D1 · 48V B0 · binds DTY1, SER12, LEU14, LYS15, ARG16
- 6XS7 · Crystal structure of human VPS29 complexed with rapid-derived cyclic peptide rt-D2 · 48V B0 · binds LYS173, DTY1, THR2, THR3, ARG14, ILE15, ARG16
- 6XS8 · Crystal structure of chaetomium thermophilum VPS29 complexed with rapid-derived cyclic… · 48V B0 · binds DTY1, ALA12
- 6XS9 · Crystal structure of human VPS29 complexed with rapid-derived cyclic peptide rt-L1 · 48V C0 · binds TYR1, ASN11, GLY14
- 6XSA · Crystal structure of human VPS29 complexed with rapid-derived cyclic peptide rt-L2 · 48V B0 · binds TYR1, LEU11, TRP12, HIS13, PRO14, LEU15
- 6YW1 · Hif prolyl hydroxylase 2 (PHD2/ EGLN1) in complex with 2OG and rapid- derived silent… · 48V B0 · binds DTY1, VAL2, SER11, ARG12, THR13
- 6YW2 · Hif prolyl hydroxylase 2 (PHD2/ EGLN1) in complex with bicyclic FG2216 and rapid-derived… · 48V B0 · binds DTY1, VAL2, SER11, ARG12, THR13
- 6YW3 · Hif prolyl hydroxylase 2 (PHD2/ EGLN1) in complex with N-oxalyl glycine (nog), hif-1ALPHA… · 48V B0 · binds LYS186, DTY1, VAL2, SER11, ARG12, THR13
- 6YW4 · Hif prolyl hydroxylase 2 (PHD2/ EGLN1) in complex with N-oxalylglycine (nog) and a… · 48V B0 · binds DTY1, VAL2, SER11, ARG12, THR13
- 7MP3 · GRB7-SH2 domain in complex with bicyclic peptide B8 · 48V L101 · binds ARG462, LYS1, PHE9, PRO10
Residues it binds most
ASP 13, LYS 17, ASN 16, GLU 12, ARG 11, GLN 12, DTY 10, PHE 10, THR 9, TYR 8 (residue and the binding sites it lines).
Found with
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