MolNFT v1 · #169533 · protein
Crystal structure of sting ref variant in complex with E7766
6XF4: “Crystal structure of sting ref variant in complex with E7766”. X-ray diffraction, 1 ligand (V5V). MolNFT v1 #169533 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 6XF4
- Type
- protein
- Length
- 351 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- UniProt
- Q86WV6
- Ligands
- V5V
Structure
x-ray diffraction · 2 distinct chains.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | — | protein | 174 | — | Q86WV6 |
| B | — | protein | 177 | — | Q86WV6 |
Ligands and binding sites
- V5V · (1R,3R,15E,28R,29R,30R,31R,34R,36R,39S,41R)-29,41-difluoro-34,39-disulfanyl-2,33,35,38,40,42-hexaoxa-4, 6,9,11,13,18,20,22,25,27-decaaza-34,39-diphosphaoctacyclo[28.6.4.1~3,36~.1~28,31~.0~4,8~.0~7, 12~.0~19,24~.0~23,27~]dotetraconta-5,7,9,11,15,19,21, 23,25-nonaene 34,39-dioxide (non-preferred name) · ligand · chains A, B
- EDO · 1,2-ethanediol · additive · 6 copies · chains A, B
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Compared structures
- 6XF4 · Crystal structure of STING REF variant in complex with E7766 · the same entry in another collection · chain A against A, TM-score 1.00
- Q86WV6 · AlphaFold monomer V2.0 prediction for stimulator of interferon genes protein (Q86WV6) · a predicted model of the same protein · chain A against A, TM-score 0.96
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q86WV6
- Elsewhere: RCSB PDB 6XF4 · PDBe 6XF4 · UniProt Q86WV6
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