AlphaFold monomer V2.0 prediction for stimulator of interferon genes protein (Q86WV6)

Structure

1 distinct chain · 54% helix, 12% strand (DSSP).

Pockets

4 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Compared structures

• 8GSZ · Structure of STING SAVI-related mutant V147L · an experimental structure of the same protein · chain A against B, TM-score 0.79
• 7SII · Human sting bound to both cgamp and 1-[(2-chloro-6-fluorophenyl)… · an experimental structure of the same protein · chain A against A, TM-score 0.50
• 4F5D · ERIS/STING in complex with ligand · an experimental structure of the same protein · chain A against A, TM-score 0.48
• 4F5D · ERIS/STING in complex with ligand · an experimental structure of the same protein · chain A against A, TM-score 0.48
• 8A2K · human STING in complex with 2'-3'-cyclic-GMP-7-deaza(4-[(2-naphthyloxy)methyl]phenyl)-AMP · an experimental structure of the same protein · chain A against A, TM-score 0.47
• 4F5W · Crystal structure of ligand free human sting ctd · an experimental structure of the same protein · chain A against A, TM-score 0.47
• 4F5W · Crystal structure of ligand free human STING CTD · an experimental structure of the same protein · chain A against A, TM-score 0.47
• 4F5Y · Crystal structure of human sting ctd complex with C-di-gmp · an experimental structure of the same protein · chain A against A, TM-score 0.47
• 4F5Y · Crystal structure of human STING CTD complex with C-di-GMP · an experimental structure of the same protein · chain A against A, TM-score 0.47
• 8A2J · human STING in complex with 2'-3'-cyclic-GMP-7-deaza(4-biphenylyl)-AMP · an experimental structure of the same protein · chain A against A, TM-score 0.47

Analyse

• Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
• Every structure of UniProt Q86WV6
• Elsewhere: UniProt Q86WV6 · AlphaFold DB Q86WV6