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AlphaFold monomer V2.0 prediction for stimulator of interferon genes protein (Q86WV6)

Analyse AlphaFold monomer V2.0 prediction for stimulator of interferon genes protein… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

Accession: Q86WV6
Type: protein
Length: 379 residues
Chains: 1
Collection: MolNFT v1 / AlphaFold
Contract: 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
Owner: 0x1Fbc4334c6ACf0E9Cee9C8366EAB84F4575214B6
Molecule: Stimulator of interferon genes protein
UniProt: Q86WV6
Pockets: 4 · best druggability 0.39

Structure

1 distinct chain · 54% helix, 12% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Stimulator of interferon genes protein	protein	379	54% helix, 12% strand	Q86WV6

Pockets

4 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	133	0.39	0.74	18	empty
2	83	0.34	0.74	14	empty
3	70	0.29	0.73	16	empty
4	60	0.28	0.74	13	empty

Compared structures

8GSZ · Structure of STING SAVI-related mutant V147L · an experimental structure of the same protein · chain A against A, TM-score 0.79
8GT6 · human STING With agonist HB3089 · an experimental structure of the same protein · chain A against A, TM-score 0.79
8IK3 · Structure of Stimulator of interferon genes/ligand complex · an experimental structure of the same protein · chain A against A, TM-score 0.52

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q86WV6
Elsewhere: UniProt Q86WV6 · AlphaFold DB Q86WV6

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