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Ligand · V5V

V5V · (1R,3R,15E,28R,29R,30R,31R,34R,36R,39S,41R)-29,41-difluoro-34,39-disulfanyl-2,33,35,38,40,42-hexaoxa-4, 6,9,11,13,18,20,22,25,27-decaaza-34,39-diphosphaoctacyclo[28.6.4.1~3,36~.1~28,31~.0~4,8~.0~7, 12~.0~19,24~.0~23,27~]dotetraconta-5,7,9,11,15,19,21, 23,25-nonaene 34,39-dioxide (non-preferred name)

V5V, (1R,3R,15E,28R,29R,30R,31R,34R,36R,39S,41R)-29,41-difluoro-34,39-disulfanyl-2,33,35,38,40,42-hexaoxa-4, 6,9,11,13,18,20,22,25,27-decaaza-34,39-diphosphaoctacyclo[28.6.4.1~3,36~.1~28,31~.0~4,8~.0~7…

Component
V5V
Formula
C24 H26 F2 N10 O8 P2 S2
Class
ligand
Structures
2
PDB entries
2

Binding sites

V5V in 2 structures; the first of them:

  • 6XF3 · Crystal structure of sting in complex with E7766 · V5V A401 · binds SER162, TYR163, GLY166, TYR167, ARG232, ILE235, ARG238, VAL239 and 15 more
  • 6XF4 · Crystal structure of sting ref variant in complex with E7766 · V5V A401 · binds SER162, TYR163, GLY166, TYR167, ILE235, ARG238, VAL239, TYR240 and 13 more

Residues it binds most

TYR 2, ARG 2, THR 2, GLY 2, ILE 2, PRO 2, SER 2, VAL 2 (residue and the binding sites it lines).

Found with

  • EDO · 1,2-ethanediol

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