MolNFT v1 · #166415 · protein
Neurotensin receptor and ARRESTIN2 complex
6UP7: “Neurotensin receptor and ARRESTIN2 complex”. Electron microscopy, 1 ligand (PIO). MolNFT v1 #166415 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 6UP7
- Type
- protein
- Length
- 685 residues
- Chains
- 4
- Method
- electron microscopy
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- UniProt
- P49407, P30989
- Ligands
- PIO
Structure
electron microscopy · 4 distinct chains.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| C | — | protein | 6 | — | — |
| B | — | protein | 348 | — | P49407 |
| R | — | protein | 322 | — | P30989 |
| V | — | protein | 9 | — | — |
Ligands and binding sites
- PIO · [(2R)-2-octanoyloxy-3-[oxidanyl-[(1R,2R,3S,4R,5R,6S)-2, 3,6-tris(oxidanyl)-4,5-diphosphonooxy-cyclohexyl]oxy-phosphoryl]oxy-propyl] octanoate · ligand · chains B, R
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Compared structures
- 6UP7 · neurotensin receptor and arrestin2 complex · the same entry in another collection · chain C against C, TM-score 1.00
- P30989 · AlphaFold monomer V2.0 prediction for neurotensin receptor type 1 (P30989) · a predicted model of the same protein · chain R against A, TM-score 0.96
- P49407 · AlphaFold monomer V2.0 prediction for beta-arrestin-1 (P49407) · a predicted model of the same protein · chain B against A, TM-score 0.90
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P49407
- Every structure of UniProt P30989
- Elsewhere: RCSB PDB 6UP7 · PDBe 6UP7 · UniProt P49407 · UniProt P30989
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