MolNFT v1 · #166008 · protein
GLUA2 in complex with its auxiliary subunit CNIH3 in as MAP II - (lbd- tmd-C3(AS) II)- with antagonist ZK200775, without ntd
6UD4: “GLUA2 in complex with its auxiliary subunit CNIH3 in as MAP II - (lbd- tmd-C3(AS) II)- with antagonist…”. Electron microscopy, 2 ligands (ZK1, CLR). MolNFT v1 #166008 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 6UD4
- Type
- protein
- Length
- 2,044 residues
- Chains
- 8
- Method
- electron microscopy
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- UniProt
- P19491, Q6ZWS4
- Ligands
- ZK1, CLR
Structure
electron microscopy · 3 distinct chains.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, B, C, D | — | protein | 378 | — | P19491 |
| E, G | — | protein | 132 | — | Q6ZWS4 |
| F, H | — | protein | 134 | — | Q6ZWS4 |
Ligands and binding sites
- ZK1 · {[7-morpholin-4-yl-2,3-dioxo-6-(trifluoromethyl)-3,4-dihydroquinoxalin-1(2H)-yl]methyl}phosphonic acid · ligand · 4 copies · chains A, B, C, D
- CLR · Cholesterol · ligand · 4 copies · chains A, E, B, F, G, C, H, D
- OLC · (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate · additive · 4 copies · chains A, F, D, B, G, H, C, E
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Compared structures
- 6UD4 · GluA2 in complex with its auxiliary subunit CNIH3 in AS map II - (LBD-TMD-C3(AS) II)… · the same entry in another collection · chain D against D, TM-score 1.00
- Q6ZWS4 · AlphaFold monomer V2.0 prediction for protein cornichon homolog 3 (Q6ZWS4) · a predicted model of the same protein · chain F against A, TM-score 0.92
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P19491
- Every structure of UniProt Q6ZWS4
- Elsewhere: RCSB PDB 6UD4 · PDBe 6UD4 · UniProt P19491 · UniProt Q6ZWS4
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