MolNFT v1 · #165230 · protein
Crystal structure of the orexin-1 receptor in complex with empa
6TOD: “Crystal structure of the orexin-1 receptor in complex with empa”. X-ray diffraction, 5 ligands (SOG, 7MA, PGW). MolNFT v1 #165230 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 6TOD
- Type
- protein
- Length
- 612 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- UniProt
- O43613
- Ligands
- SOG, 7MA, PGW, NA, SO4
Structure
x-ray diffraction · 2 distinct chains.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | — | protein | 301 | — | O43613 |
| B | — | protein | 311 | — | O43613 |
Ligands and binding sites
- SOG · octyl 1-thio-beta-D-glucopyranoside · ligand · 47 copies · chains A, B
- 7MA · N-ethyl-2-[(6-methoxypyridin-3-yl)-(2-methylphenyl) sulfonyl-amino]-N-(pyridin-3-ylmethyl)ethanamide · ligand · 2 copies · chains A, B
- PGW · (1R)-2-{[(S)-{[(2S)-2,3-dihydroxypropyl]oxy}(hydroxy) phosphoryl]oxy}-1-[(hexadecanoyloxy)methyl]ethyl (9Z)-octadec-9-enoate · ligand · 2 copies · chains A, B
- NA · Sodium ion · metal · 2 copies · chains A, B
- SO4 · Sulfate ion · ion · 3 copies · chains A, B
- PG4 · Tetraethylene glycol · additive · 5 copies · chains A, B
- CIT · Citric acid · additive · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Compared structures
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt O43613
- Elsewhere: RCSB PDB 6TOD · PDBe 6TOD · UniProt O43613
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