MolNFT v1 · #165220 · protein + DNA
Human polymerase delta-FEN1-PCNA toolbelt
6TNZ: “Human polymerase delta-FEN1-PCNA toolbelt”. Electron microscopy, 3 ligands (SF4, TTP, ZN). MolNFT v1 #165220 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 6TNZ
- Type
- protein + DNA
- Length
- 2,755 residues
- Chains
- 10
- Method
- electron microscopy
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- UniProt
- P28340, P49005, Q15054, Q9HCU8, P12004, P39748
- Ligands
- SF4, TTP, ZN
Structure
electron microscopy · 10 distinct chains.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | — | protein | 1010 | — | P28340 |
| B | — | protein | 431 | — | P49005 |
| C | — | protein | 143 | — | Q15054 |
| D | — | protein | 66 | — | Q9HCU8 |
| E | — | protein | 251 | — | P12004 |
| F | — | protein | 249 | — | P12004 |
| G | — | protein | 249 | — | P12004 |
| H | — | protein | 306 | — | P39748 |
| P | — | dna | 23 | — | — |
| T | — | dna | 27 | — | — |
Ligands and binding sites
- SF4 · Iron/sulfur cluster · ligand · chains A
- TTP · Thymidine-5'-triphosphate · ligand · chains A, P, T
- ZN · Zinc ion · metal · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Compared structures
- 6TNZ · Human polymerase delta-FEN1-PCNA toolbelt · the same entry in another collection · chain T against T, TM-score 1.00
- Q15054 · AlphaFold monomer V2.0 prediction for DNA polymerase delta subunit 3 (Q15054) · a predicted model of the same protein · chain C against A, TM-score 0.96
- P49005 · AlphaFold monomer V2.0 prediction for DNA polymerase delta subunit 2 (P49005) · a predicted model of the same protein · chain B against A, TM-score 0.95
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P28340
- Every structure of UniProt P49005
- Every structure of UniProt Q15054
- Every structure of UniProt Q9HCU8
- Every structure of UniProt P12004
- Every structure of UniProt P39748
- Elsewhere: RCSB PDB 6TNZ · PDBe 6TNZ · UniProt P28340 · UniProt P49005 · UniProt Q15054 · UniProt Q9HCU8 · UniProt P12004 · UniProt P39748
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