UniProt Q9HCU8
DNA polymerase delta subunit 4 (Q9HCU8)
DNA polymerase delta subunit 4 (UniProt Q9HCU8): 12 experimental structures and 1 predicted model on GenesisL1, 1 ligand bound, 7 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q9HCU8
- Protein
- DNA polymerase delta subunit 4
- Experimental structures
- 12
- Predicted models
- 1
- Ligands
- 1
- Pockets
- 7 · 5 records with a druggable one
Structures
13 records of Q9HCU8 in the MolNFT archive: 12 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 6HVO | Crystal structure of human PCNA in complex with three peptides of p12 subunit of human polymerase… | x-ray diffraction | D, F, E | SO4 | — |
| 6HVO | Crystal structure of human PCNA in complex with three peptides of P12 subunit of human polymerase… | x-ray diffraction | D, F, E | SO4 | — |
| 6S1M | Human polymerase delta holoenzyme Conformer 1 | electron microscopy | D | — | 2 (best 0.80) |
| 6S1M | Human polymerase delta holoenzyme conformer 1 | electron microscopy | D | — | — |
| 6S1N | Human polymerase delta holoenzyme Conformer 2 | electron microscopy | D | — | 1 (best 0.80) |
| 6S1N | Human polymerase delta holoenzyme conformer 2 | electron microscopy | D | — | — |
| 6S1O | Human polymerase delta holoenzyme Conformer 3 | electron microscopy | D | — | 1 (best 0.79) |
| 6S1O | Human polymerase delta holoenzyme conformer 3 | electron microscopy | D | — | — |
| 6TNY | Processive human polymerase delta holoenzyme | electron microscopy | D | — | 2 (best 0.74) |
| 6TNY | Processive human polymerase delta holoenzyme | electron microscopy | D | — | — |
| 6TNZ | Human polymerase delta-FEN1-PCNA toolbelt | electron microscopy | D | — | 1 (best 0.80) |
| 6TNZ | Human polymerase delta-FEN1-PCNA toolbelt | electron microscopy | D | — | — |
| Q9HCU8 | AlphaFold monomer V2.0 prediction for DNA polymerase delta subunit 4 (Q9HCU8) | predicted | A | — | — |
Ligands
- SO4 · Sulfate ion · in 2 records
Experiment against prediction
- 6S1O chain D against the predicted model Q9HCU8: TM-score 0.93, RMSD 0.78 Å
- 6S1O chain D against the predicted model Q9HCU8: TM-score 0.93, RMSD 0.78 Å
- 6TNY chain D against the predicted model Q9HCU8: TM-score 0.93, RMSD 0.78 Å
- 6TNY chain D against the predicted model Q9HCU8: TM-score 0.93, RMSD 0.78 Å
- 6TNZ chain D against the predicted model Q9HCU8: TM-score 0.93, RMSD 0.78 Å
- 6TNZ chain D against the predicted model Q9HCU8: TM-score 0.93, RMSD 0.78 Å
- 6S1M chain D against the predicted model Q9HCU8: TM-score 0.93, RMSD 0.78 Å
- 6S1M chain D against the predicted model Q9HCU8: TM-score 0.93, RMSD 0.78 Å
- 6S1N chain D against the predicted model Q9HCU8: TM-score 0.93, RMSD 0.78 Å
- 6S1N chain D against the predicted model Q9HCU8: TM-score 0.93, RMSD 0.78 Å
Elsewhere
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