UniProt P12004
Proliferating cell nuclear antigen (P12004)
Proliferating cell nuclear antigen (UniProt P12004): 105 experimental structures on GenesisL1, 7 ligands bound, 205 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.
- UniProt
- P12004
- Protein
- Proliferating cell nuclear antigen
- Experimental structures
- 105
- Predicted models
- 0
- Ligands
- 7
- Pockets
- 205 · 18 records with a druggable one
Structures
105 records of P12004 in the MolNFT archive: 105 experimental, 0 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1AXC | HUMAN PCNA | x-ray diffraction | A, C, E | — | — |
| 1AXC | HUMAN PCNA | x-ray diffraction | A, C, E | — | — |
| 1U76 | Crystal structure of hPCNA bound to residues 452-466 of the DNA polymerase-delta-p66 subunit | x-ray diffraction | A, C, E | — | — |
| 1U76 | Crystal structure of hpcna bound to residues 452-466 of the DNA polymerase-delta-P66 subunit | x-ray diffraction | A, C, E | — | — |
| 1U7B | Crystal structure of hPCNA bound to residues 331-350 of the flap endonuclease-1 (FEN1) | x-ray diffraction | A | — | — |
| 1U7B | Crystal structure of hpcna bound to residues 331-350 of the flap endonuclease-1 (FEN1) | x-ray diffraction | A | — | — |
| 1UL1 | Crystal structure of the human FEN1-PCNA complex | x-ray diffraction | A, B, C | — | — |
| 1UL1 | Crystal structure of the human FEN1-PCNA complex | x-ray diffraction | A, B, C | — | — |
| 1VYJ | Structural and biochemical studies of human PCNA complexes provide the basis for association with… | x-ray diffraction | A, C, E, G, I, K | — | — |
| 1VYJ | Structural and biochemical studies of human PCNA complexes provide the basis for association with… | x-ray diffraction | A, C, E, G, I, K | — | — |
| 1VYM | Native human PCNA | x-ray diffraction | A, B, C | — | — |
| 1VYM | Native human PCNA | x-ray diffraction | A, B, C | — | — |
| 1W60 | Native human PCNA | x-ray diffraction | A, B | — | — |
| 1W60 | Native human PCNA | x-ray diffraction | A, B | — | — |
| 2ZVK | Crystal structure of PCNA in complex with DNA polymerase eta fragment | x-ray diffraction | A, B, C | — | — |
| 2ZVK | Crystal structure of PCNA in complex with DNA polymerase eta fragment | x-ray diffraction | A, B, C | — | — |
| 2ZVL | Crystal structure of PCNA in complex with DNA polymerase kappa fragment | x-ray diffraction | A, B, C, D, E, F | — | — |
| 2ZVL | Crystal structure of PCNA in complex with DNA polymerase kappa fragment | x-ray diffraction | A, B, C, D, E, F | — | — |
| 2ZVM | Crystal structure of PCNA in complex with DNA polymerase iota fragment | x-ray diffraction | A, B, C | — | — |
| 2ZVM | Crystal structure of PCNA in complex with DNA polymerase iota fragment | x-ray diffraction | A, B, C | — | — |
| 3JA9 | Structure of native human PCNA | electron microscopy | A, B, C | — | — |
| 3JA9 | Structure of native human PCNA | electron microscopy | A, B, C | — | — |
| 3P87 | Structure of human PCNA bound to RNASEH2B PIP box peptide | x-ray diffraction | A, B, C, D, E, F | — | — |
| 3P87 | Structure of human PCNA bound to RNASEH2B pip box peptide | x-ray diffraction | A, B, C, D, E, F | — | — |
| 3TBL | Structure of Mono-ubiquitinated PCNA: Implications for DNA Polymerase Switching and Okazaki… | x-ray diffraction | A, B, C | — | — |
| 3TBL | Structure of mono-ubiquitinated PCNA: implications for DNA polymerase switching and okazaki… | x-ray diffraction | A, B, C | — | — |
| 3VKX | Structure of PCNA | x-ray diffraction | A | — | — |
| 3VKX | Structure of PCNA | x-ray diffraction | A | — | — |
| 3WGW | Structure of PCNA bound to a small molecule inhibitor | x-ray diffraction | A, B | — | — |
| 3WGW | Structure of PCNA bound to a small molecule inhibitor | x-ray diffraction | A, B | — | — |
| 4D2G | Crystal structure of human PCNA in complex with p15 peptide | x-ray diffraction | A, B, C | — | — |
| 4D2G | Crystal structure of human PCNA in complex with P15 peptide | x-ray diffraction | A, B, C | — | — |
| 4RJF | Crystal structure of the human sliding clamp at 2.0 angstrom resolution | x-ray diffraction | A, C, E | — | — |
| 4RJF | Crystal structure of the human sliding clamp at 2.0 ångström resolution | x-ray diffraction | A, C, E | — | — |
| 4ZTD | Crystal Structure of Human PCNA in complex with a TRAIP peptide | x-ray diffraction | A, B, C | — | 5 (best 0.47) |
| 4ZTD | Crystal structure of human PCNA in complex with a traip peptide | x-ray diffraction | A, B, C | — | — |
| 5E0T | Human PCNA mutant - S228I | x-ray diffraction | A, B, C | — | 5 (best 0.44) |
| 5E0T | Human PCNA mutant - S228I | x-ray diffraction | A, B, C | — | — |
| 5E0U | Human PCNA variant (S228I) complexed with p21 at 1.9 Angstroms | x-ray diffraction | A, B, C | — | 8 (best 0.69) |
| 5E0U | Human PCNA variant (S228I) complexed with P21 at 1.9 ångströms | x-ray diffraction | A, B, C | — | — |
| 5E0V | Human PCNA variant (S228I) complexed with FEN1 at 2.1 Angstroms | x-ray diffraction | A, B | — | 3 (best 0.57) |
| 5E0V | Human PCNA variant (S228I) complexed with FEN1 at 2.1 ångströms | x-ray diffraction | A, B | — | — |
| 5IY4 | Crystal structure of human PCNA in complex with the PIP box of DVC1 | x-ray diffraction | A, C, E | — | 4 (best 0.45) |
| 5IY4 | Crystal structure of human PCNA in complex with the pip box of DVC1 | x-ray diffraction | A, C, E | — | — |
| 5MAV | Crystal structure of human PCNA in complex with PARG (poly(ADP-ribose) glycohydrolase) peptide. | x-ray diffraction | A, C, E, B, D, F | — | — |
| 5MAV | Crystal structure of human PCNA in complex with parg (POLY(ADP-ribose) glycohydrolase) peptide. | x-ray diffraction | A, C, E, B, D, F | — | — |
| 5MLO | Crystal structure of human PCNA in complex with ZRANB3 pip box peptide | x-ray diffraction | A, C, E | NA | — |
| 5MLW | Crystal structure of human PCNA in complex with ZRANB3 APIM motif peptide | x-ray diffraction | A, C, E | SO4 | 9 (best 0.37) |
| 5MLW | Crystal structure of human PCNA in complex with ZRANB3 apim motif peptide | x-ray diffraction | A, C, E | SO4 | — |
| 5MOM | Crystal Structure of PCNA encoding the hypomorphic mutation S228I | x-ray diffraction | A, B, C | — | 5 (best 0.40) |
| 5MOM | Crystal structure of PCNA encoding the hypomorphic mutation S228I | x-ray diffraction | A, B, C | — | — |
| 5YCO | Complex structure of PCNA with UHRF2 | x-ray diffraction | A, B, C, D | SO4 | — |
| 5YD8 | Crystal structure of human PCNA in complex with apim of human ZRANB3 | x-ray diffraction | Y, X, Z | — | — |
| 6CBI | PCNA in complex with inhibitor | x-ray diffraction | A, C, E, B, D, F | SO4 | 19 (best 0.73) |
| 6CBI | PCNA in complex with inhibitor | x-ray diffraction | A, C, E, B, D, F | SO4 | — |
| 6EHT | Modulation of PCNA sliding surface by P15PAF suggests a suppressive mechanism for cisplatin-induced… | x-ray diffraction | A, B, C | — | — |
| 6FCM | Crystal structure of human PCNA | x-ray diffraction | A, C, E | — | — |
| 6FCM | Crystal structure of human PCNA | x-ray diffraction | A, C, E | — | — |
| 6FCN | Crystal structure of human PCNA soaked with p47phox(106-127) peptide | x-ray diffraction | A, C, E | — | 5 (best 0.45) |
| 6FCN | Crystal structure of human PCNA soaked with P47PHOX(106-127) peptide | x-ray diffraction | A, C, E | — | — |
45 records more on the page itself.
Ligands
- SO4 · Sulfate ion · in 6 records
- CL · Chloride ion · in 2 records
- 8VH · 1,3-dimethylbenzene · in 1 record
- NA · Sodium ion · in 1 record
- NH2 · Amino group · in 1 record
- ZQW · N~2~-(naphthalene-1-carbonyl)-N-(2-phenoxyphenyl)-L-alpha-glutamine · in 1 record
- ZQZ · N-[2-(3-methoxyphenoxy)phenyl]-N~2~-(naphthalene-1-carbonyl)-L-alpha-glutamine · in 1 record
Elsewhere
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