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MolNFT v1 · #165080 · protein

Drosophila GDP-tubulin Y222F mutant

6TIZ: “Drosophila GDP-tubulin Y222F mutant”. X-ray diffraction, 4 ligands (GTP, GDP, MG). MolNFT v1 #165080 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB
6TIZ
Type
protein
Length
1,844 residues
Chains
5
Method
x-ray diffraction
Collection
MolNFT v1 / PDB
Contract
0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner
0x3396CDB397284571d12822B4ae1189a8E22AAAAA
UniProt
P06603, Q24560, P63043
Ligands
GTP, GDP, MG, SO4

Structure

x-ray diffraction · 5 distinct chains.

ChainMoleculeTypeResiduesSecondary structureUniProt
A—protein430—P06603
B—protein428—Q24560
C—protein430—P06603
D—protein427—Q24560
E—protein129—P63043

Ligands and binding sites

  • GTP · Guanosine-5'-triphosphate · ligand · 2 copies · chains A, B, C, D
  • GDP · Guanosine-5'-diphosphate · ligand · 2 copies · chains B, D
  • MG · Magnesium ion · metal · 2 copies · chains B, D
  • SO4 · Sulfate ion · ion · 13 copies · chains A, B, C, D, E
  • GOL · Glycerol · additive · 2 copies · chains A, E

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Compared structures

  • 6TIZ · Drosophila GDP-tubulin Y222F mutant · the same entry in another collection · chain E against E, TM-score 1.00
  • Q24560 · AlphaFold monomer V2.0 prediction for tubulin beta-1 chain (Q24560) · a predicted model of the same protein · chain B against A, TM-score 0.98
  • P06603 · AlphaFold monomer V2.0 prediction for tubulin alpha-1 chain (P06603) · a predicted model of the same protein · chain C against A, TM-score 0.98

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