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UniProt P06603

Tubulin alpha-1 chain (P06603)

Tubulin alpha-1 chain (UniProt P06603): 11 experimental structures on GenesisL1, 4 ligands bound, 67 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.

UniProt
P06603
Protein
Tubulin alpha-1 chain
Experimental structures
11
Predicted models
0
Ligands
4
Pockets
67 · 6 records with a druggable one

Structures

11 records of P06603 in the MolNFT archive: 11 experimental, 0 predicted.

EntryTitleMethodChainsLigandsPockets
6TISDrosophila GDP-tubulinx-ray diffractionA, CGTP, SO4—
6TIUDrosophila GTP-tubulin Y222F mutantx-ray diffractionA, CGTP, MG, SO416 (best 0.82)
6TIUDrosophila GTP-tubulin Y222F mutantx-ray diffractionA, CGTP, MG, SO4—
6TIYDrosophila gmpcpp-tubulinx-ray diffractionA, CGTP, MG, SO4—
6TIZDrosophila GDP-tubulin Y222F mutantx-ray diffractionA, CGTP, SO4—
7QUCD. melanogaster alpha/beta tubulin heterodimer in the GDP formelectron microscopyAGTP, MG4 (best 0.81)
7QUDD. melanogaster alpha/beta tubulin heterodimer in the GTP formelectron microscopyAGTP, MG7 (best 0.78)
7QUPD. melanogaster 13-protofilament microtubuleelectron microscopy10A, 10C, 10E, 11A, 11C, 11E, 12A, 12C, 12E, 13A, 13C, 13E, 1A, 1C, 1E, 2A, 2C, 2E, 3A, 3C, 3E, 4A, 4C, 4E, 5A, 5C, 5E, 6A, 6C, 6E, 7A, 7C, 7E, 8A, 8C, 8E, 9A, 9C, 9EGTP, MG, GDP20 (best 0.86)
7YSQGTPgammaS Tube decorated with kinesinelectron microscopyA, D, E, FGTP10 (best 0.86)
7YSRGTPgammaS MT decorated with kinesinelectron microscopyA, CGTP10 (best 0.82)
P06603AlphaFold monomer V2.0 prediction for tubulin alpha-1 chain (P06603)———

Ligands

  • GTP · Guanosine-5'-triphosphate · in 10 records
  • MG · Magnesium ion · in 6 records
  • SO4 · Sulfate ion · in 5 records
  • GDP · Guanosine-5'-diphosphate · in 1 record

Elsewhere

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