MolNFT v1 · #163225 · protein
Fragment az-007 binding at a primary and secondary binding site of the the P53PT387/14-3-3 sigma complex
6RWH: “Fragment az-007 binding at a primary and secondary binding site of the the P53PT387/14-3-3 sigma complex”. X-ray diffraction, 3 ligands (KLB, MG, CA). MolNFT v1 #163225 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 6RWH
- Type
- protein
- Length
- 239 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- UniProt
- P31947, P04637
- Ligands
- KLB, MG, CA
Structure
x-ray diffraction · 2 distinct chains.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | — | protein | 227 | — | P31947 |
| P | — | protein | 12 | — | P04637 |
Ligands and binding sites
- KLB · 5-(1~{H}-imidazol-5-yl)-4-phenyl-thiophene-2-carboximidamide · ligand · 2 copies · chains A
- MG · Magnesium ion · metal · 2 copies · chains A, P
- CA · Calcium ion · metal · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Compared structures
- 6RWH · Fragment AZ-007 binding at a primary and secondary binding site of the the… · the same entry in another collection · chain A against A, TM-score 1.00
- P31947 · AlphaFold monomer V2.0 prediction for 14-3-3 protein sigma (P31947) · a predicted model of the same protein · chain A against A, TM-score 0.96
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P31947
- Every structure of UniProt P04637
- Elsewhere: RCSB PDB 6RWH · PDBe 6RWH · UniProt P31947 · UniProt P04637
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