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MolNFT v1 · #156331 · protein

X-ray structure of drosophila dopamine transporter with subsiteb mutations (D121G/S426M) in substrate-free form

6M0F: “X-ray structure of drosophila dopamine transporter with subsiteb mutations (D121G/S426M) in substrate-free…”. X-ray diffraction, 4 ligands (CLR, P4G, NA). MolNFT v1 #156331 on GenesisL1: 3D structure, binding sites and pockets in…

PDB
6M0F
Type
protein
Length
967 residues
Chains
3
Method
x-ray diffraction
Collection
MolNFT v1 / PDB
Contract
0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner
0x3396CDB397284571d12822B4ae1189a8E22AAAAA
UniProt
Q7K4Y6
Ligands
CLR, P4G, NA, CL

Structure

x-ray diffraction · 3 distinct chains.

ChainMoleculeTypeResiduesSecondary structureUniProt
A—protein534—Q7K4Y6
L—protein214——
H—protein219——

Ligands and binding sites

  • CLR · Cholesterol · ligand · 2 copies · chains A
  • P4G · 1-ethoxy-2-(2-ethoxyethoxy)ethane · ligand · chains A
  • NA · Sodium ion · metal · 2 copies · chains A
  • CL · Chloride ion · ion · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Compared structures

  • 6M0F · X-ray structure of Drosophila dopamine transporter with subsiteB mutations (D121G/S426M)… · the same entry in another collection · chain A against A, TM-score 1.00
  • Q7K4Y6 · AlphaFold monomer V2.0 prediction for sodium-dependent dopamine transporter (Q7K4Y6) · a predicted model of the same protein · chain A against A, TM-score 0.99

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