MolNFT v1 · #150991 · protein

Factor inhibiting hif (fih) in complex with zinc, nog and TRPV3 (220- 246)

6HA6: “Factor inhibiting hif (fih) in complex with zinc, nog and TRPV3 (220- 246)”. X-ray diffraction, 3 ligands (OGA, ZN, SO4). MolNFT v1 #150991 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 6HA6
Type: protein
Length: 354 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
UniProt: Q9NWT6, Q8NET8
Ligands: OGA, ZN, SO4

Structure

x-ray diffraction · 2 distinct chains.

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	—	protein	340	—	Q9NWT6
D	—	protein	14	—	Q8NET8

Ligands and binding sites

OGA · N-oxalylglycine · ligand · chains A
ZN · Zinc ion · metal · chains A
SO4 · Sulfate ion · ion · 4 copies · chains A
GOL · Glycerol · additive · 3 copies · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Compared structures

6HA6 · Factor Inhibiting HIF (FIH) in complex with zinc, NOG and TRPV3 (220-246) · the same entry in another collection · chain A against A, TM-score 1.00
Q9NWT6 · AlphaFold monomer V2.0 prediction for hypoxia-inducible factor 1-alpha inhibitor (Q9NWT6) · a predicted model of the same protein · chain A against A, TM-score 0.95
Q8NET8 · AlphaFold monomer V2.0 prediction for transient receptor potential cation channel… · a predicted model of the same protein · chain D against A, TM-score 0.41

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q9NWT6
Every structure of UniProt Q8NET8
Elsewhere: RCSB PDB 6HA6 · PDBe 6HA6 · UniProt Q9NWT6 · UniProt Q8NET8

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