GL1X · GenesisL1 explorer

MolNFT v1 · #147263 · protein

Structure of the lipoprotein lipase GPIHBP1 complex that mediates plasma triglyceride hydrolysis

6E7K: “Structure of the lipoprotein lipase GPIHBP1 complex that mediates plasma triglyceride hydrolysis”. X-ray diffraction, 4 ligands (NAG, BMA, FUC). MolNFT v1 #147263 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB
6E7K
Type
protein
Length
1,007 residues
Chains
4
Method
x-ray diffraction
Collection
MolNFT v1 / PDB
Contract
0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner
0x3396CDB397284571d12822B4ae1189a8E22AAAAA
UniProt
P06858, Q8IV16
Ligands
NAG, BMA, FUC, CA

Structure

x-ray diffraction · 4 distinct chains.

ChainMoleculeTypeResiduesSecondary structureUniProt
A—protein421—P06858
B—protein422—P06858
C—protein83—Q8IV16
D—protein81—Q8IV16

Ligands and binding sites

  • NAG · 2-acetamido-2-deoxy-beta-D-glucopyranose · sugar · 8 copies · chains A, B, C
  • BMA · beta-D-mannopyranose · sugar · 2 copies
  • FUC · alpha-L-fucopyranose · sugar · 2 copies · chains A, B
  • CA · Calcium ion · metal · 2 copies · chains A, B

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Compared structures

  • 6E7K · Structure of the lipoprotein lipase GPIHBP1 complex that mediates plasma triglyceride… · the same entry in another collection · chain D against D, TM-score 1.00
  • P06858 · AlphaFold monomer V2.0 prediction for lipoprotein lipase (P06858) · a predicted model of the same protein · chain B against A, TM-score 0.99
  • Q8IV16 · AlphaFold monomer V2.0 prediction for glycosylphosphatidylinositol- anchored high density… · a predicted model of the same protein · chain D against A, TM-score 0.98

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