Research workbench
Structure of the lipoprotein lipase GPIHBP1 complex that mediates plasma triglyceride hydrolysis
Analyse Structure of the lipoprotein lipase GPIHBP1 complex that mediates plasma… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 6E7K
- Type
- protein
- Length
- 1,007 residues
- Chains
- 4
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- UniProt
- P06858, Q8IV16
- Ligands
- NAG, BMA, FUC, CA
Structure
x-ray diffraction · 4 distinct chains.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | — | protein | 421 | — | P06858 |
| B | — | protein | 422 | — | P06858 |
| C | — | protein | 83 | — | Q8IV16 |
| D | — | protein | 81 | — | Q8IV16 |
Ligands and binding sites
- NAG · 2-acetamido-2-deoxy-beta-D-glucopyranose · sugar · 8 copies · chains A, B, C
- BMA · beta-D-mannopyranose · sugar · 2 copies
- FUC · alpha-L-fucopyranose · sugar · 2 copies · chains A, B
- CA · Calcium ion · metal · 2 copies · chains A, B
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Compared structures
- 6E7K · Structure of the lipoprotein lipase GPIHBP1 complex that mediates plasma triglyceride… · the same entry in another collection · chain D against D, TM-score 1.00
- P06858 · AlphaFold monomer V2.0 prediction for lipoprotein lipase (P06858) · a predicted model of the same protein · chain B against A, TM-score 0.99
- Q8IV16 · AlphaFold monomer V2.0 prediction for glycosylphosphatidylinositol- anchored high density… · a predicted model of the same protein · chain D against A, TM-score 0.98
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P06858
- Every structure of UniProt Q8IV16
- Elsewhere: RCSB PDB 6E7K · PDBe 6E7K · UniProt P06858 · UniProt Q8IV16
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