UniProt Q8IV16
Glycosylphosphatidylinositol-anchored high density lipoprotein-binding protein 1 (Q8IV16)
Glycosylphosphatidylinositol-anchored high density lipoprotein-binding protein 1 (UniProt Q8IV16): 8 experimental structures and 1 predicted model on GenesisL1, 2 ligands bound, 24 pockets. Binding sites, druggability and…
- UniProt
- Q8IV16
- Protein
- Glycosylphosphatidylinositol-anchored high density lipoprotein-binding protein 1
- Experimental structures
- 8
- Predicted models
- 1
- Ligands
- 2
- Pockets
- 24 · 2 records with a druggable one
Structures
9 records of Q8IV16 in the MolNFT archive: 8 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 6E7K | Structure of the lipoprotein lipase GPIHBP1 complex that mediates plasma triglyceride hydrolysis | x-ray diffraction | C, D | NAG | 4 (best 0.43) |
| 6E7K | Structure of the lipoprotein lipase GPIHBP1 complex that mediates plasma triglyceride hydrolysis | x-ray diffraction | C, D | NAG | — |
| 6OAU | Apo Structure of WT Lipoprotein Lipase in Complex with GPIHBP1 Mutant N78D N82D produced in… | x-ray diffraction | C, D | — | 4 (best 0.45) |
| 6OAU | Apo structure of wt lipoprotein lipase in complex with GPIHBP1 mutant N78D N82D produced in… | x-ray diffraction | C, D | — | — |
| 6OAZ | Apo Structure of WT Lipoprotein Lipase in Complex with GPIHBP1 Mutant N78D N82D produced in… | x-ray diffraction | E, F, G, H | CA | 8 (best 0.62) |
| 6OAZ | Apo structure of wt lipoprotein lipase in complex with GPIHBP1 mutant N78D N82D produced in… | x-ray diffraction | E, F, G, H | CA | — |
| 6OB0 | Compound 2 bound structure of WT Lipoprotein Lipase in Complex with GPIHBP1 Mutant N78D N82D… | x-ray diffraction | E, F, G, H | — | 8 (best 0.63) |
| 6OB0 | Compound 2 bound structure of wt lipoprotein lipase in complex with GPIHBP1 mutant N78D N82D… | x-ray diffraction | E, F, G, H | — | — |
| Q8IV16 | AlphaFold monomer V2.0 prediction for glycosylphosphatidylinositol- anchored high density… | predicted | A | — | — |
Ligands
Experiment against prediction
- 6OAU chain C against the predicted model Q8IV16: TM-score 0.99, RMSD 0.33 Å
- 6OAU chain C against the predicted model Q8IV16: TM-score 0.99, RMSD 0.33 Å
- 6OAZ chain G against the predicted model Q8IV16: TM-score 0.99, RMSD 0.35 Å
- 6OAZ chain G against the predicted model Q8IV16: TM-score 0.99, RMSD 0.35 Å
- 6OAZ chain H against the predicted model Q8IV16: TM-score 0.99, RMSD 0.35 Å
- 6OAZ chain H against the predicted model Q8IV16: TM-score 0.99, RMSD 0.35 Å
- 6OB0 chain F against the predicted model Q8IV16: TM-score 0.99, RMSD 0.36 Å
- 6OB0 chain F against the predicted model Q8IV16: TM-score 0.99, RMSD 0.36 Å
- 6OAU chain D against the predicted model Q8IV16: TM-score 0.99, RMSD 0.40 Å
- 6OAU chain D against the predicted model Q8IV16: TM-score 0.99, RMSD 0.40 Å
Elsewhere
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