MolNFT v1 · #147091 · protein

Ternary structure of C-myc-tbp-TAF1

6E24 · Transcription initiation factor tfiid subunit 1,MYC proto…: “Ternary structure of C-myc-tbp-TAF1”. X-ray diffraction, 2 pockets (best druggability 0.46). MolNFT v1 #147091 on GenesisL1: 3D structure, binding sites and pockets in…

PDB: 6E24
Type: protein
Length: 219 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Transcription initiation factor tfiid subunit 1,MYC proto- oncogene…
EC: 2.3.1.48
UniProt: P46677, P01106, P13393
Pockets: 2 · best druggability 0.46

Structure

x-ray diffraction · 1 distinct chain · 34% helix, 30% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Transcription initiation factor tfiid subunit 1,MYC proto- oncogene PROTEIN,TATA-box-binding protein (EC 2.3.1.48)	protein	219	34% helix, 30% strand	P46677, P01106, P13393

Pockets

2 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	159	0.46	0.76	24	empty
2	77	0.30	0.73	16	empty

Compared structures

6E24 · Ternary structure of c-Myc-TBP-TAF1 · the same entry in another collection · chain A against A, TM-score 1.00
P13393 · AlphaFold monomer V2.0 prediction for tata-box-binding protein (P13393) · a predicted model of the same protein · chain A against A, TM-score 0.85
P46677 · AlphaFold monomer V2.0 prediction for transcription initiation factor tfiid subunit 1… · a predicted model of the same protein · chain A against A, TM-score 0.29
P01106 · AlphaFold monomer V2.0 prediction for myc proto-oncogene protein (P01106) · a predicted model of the same protein · chain A against A, TM-score 0.21

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P46677
Every structure of UniProt P01106
Every structure of UniProt P13393
Elsewhere: RCSB PDB 6E24 · PDBe 6E24 · UniProt P46677 · UniProt P01106 · UniProt P13393

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.