UniProt P46677
Transcription initiation factor tfiid subunit 1 (P46677)
Transcription initiation factor tfiid subunit 1 (UniProt P46677), EC 2.3.1.48: 7 experimental structures and 1 predicted model on GenesisL1, 14 pockets. Binding sites, druggability and experiment against prediction (TM-score) in…
- UniProt
- P46677
- Protein
- Transcription initiation factor tfiid subunit 1
- EC
- 2.3.1.48
- Experimental structures
- 7
- Predicted models
- 1
- Pockets
- 14 · 1 record with a druggable one
Structures
8 records of P46677 in the MolNFT archive: 7 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 4B0A | The high-resolution structure of yTBP-yTAF1 identifies conserved and competing interaction surfaces… | x-ray diffraction | A | — | — |
| 4B0A | The high-resolution structure of ytbp-YTAF1 identifies conserved and competing interaction surfaces… | x-ray diffraction | A | — | — |
| 4OY2 | Crystal structure of TAF1-TAF7, a TFIID subcomplex | x-ray diffraction | A, C, E | — | — |
| 4OY2 | Crystal structure of TAF1-TAF7, a tfiid subcomplex | x-ray diffraction | A, C, E | — | — |
| 6E16 | Ternary structure of C-myc-tbp-TAF1 | x-ray diffraction | A | — | — |
| 6E24 | Ternary structure of c-Myc-TBP-TAF1 | x-ray diffraction | A | — | 2 (best 0.46) |
| 6E24 | Ternary structure of C-myc-tbp-TAF1 | x-ray diffraction | A | — | — |
| P46677 | AlphaFold monomer V2.0 prediction for transcription initiation factor tfiid subunit 1 (P46677) | predicted | A | — | 12 (best 0.71) |
Experiment against prediction
- 4OY2 chain C against the predicted model P46677: TM-score 0.98, RMSD 1.24 Å
- 4OY2 chain C against the predicted model P46677: TM-score 0.98, RMSD 1.24 Å
- 4OY2 chain A against the predicted model P46677: TM-score 0.98, RMSD 1.26 Å
- 4OY2 chain A against the predicted model P46677: TM-score 0.98, RMSD 1.26 Å
- 4OY2 chain E against the predicted model P46677: TM-score 0.96, RMSD 1.79 Å
- 4OY2 chain E against the predicted model P46677: TM-score 0.96, RMSD 1.79 Å
- 6E16 chain A against the predicted model P46677: TM-score 0.30, RMSD 5.87 Å
- 6E24 chain A against the predicted model P46677: TM-score 0.29, RMSD 5.81 Å
- 6E24 chain A against the predicted model P46677: TM-score 0.29, RMSD 5.81 Å
- 4B0A chain A against the predicted model P46677: TM-score 0.27, RMSD 6.89 Å
Elsewhere
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