MolNFT v1 · #142190 · protein
FAD-piga complex at 1.3 a
5ZW7 · L-prolyl-[peptidyl-carrier protein] dehydrogenase: “FAD-piga complex at 1.3 a”. X-ray diffraction, 3 ligands (FAD, O4B, CL), 4 pockets (best druggability 0.71). MolNFT v1 #142190 on GenesisL1: 3D structure, binding sites and pockets…
- PDB
- 5ZW7
- Type
- protein
- Length
- 383 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- L-prolyl-[peptidyl-carrier protein] dehydrogenase
- EC
- 1.3.8.14
- UniProt
- Q5W271
- Ligands
- FAD, O4B, CL
- Pockets
- 4 · best druggability 0.71
Structure
x-ray diffraction · 1 distinct chain · 58% helix, 15% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | L-prolyl-[peptidyl-carrier protein] dehydrogenase (EC 1.3.8.14) | protein | 383 | 58% helix, 15% strand | Q5W271 |
Ligands and binding sites
- FAD · Flavin-adenine dinucleotide · ligand · chains A
- O4B · 1,4,7,10,13,16-hexaoxacyclooctadecane · ligand · chains A
- CL · Chloride ion · ion · chains A
- GOL · Glycerol · additive · 5 copies · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
4 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 401 | 0.71 | 0.82 | 45 | FAD, GOL |
| 2 | 150 | 0.69 | 0.89 | 25 | GOL |
| 3 | 72 | 0.33 | 0.74 | 11 | empty |
| 4 | 58 | 0.27 | 0.74 | 16 | empty |
Compared structures
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q5W271
- Elsewhere: RCSB PDB 5ZW7 · PDBe 5ZW7 · UniProt Q5W271
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